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Why might the finding of a new genetic association with inflammatory bowel disease be of potential value in disease control?
new genetic association inflammatory bowel disease potential value disease control
2018/11/20
Inflammatory bowel disease (IBD) has long been recognized as an exaggerated inflammatory response to common antigenic stimuli in the gut. Ulcerative colitis (UC) (1) and Crohn disease (CD) (2) are the...
Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals
nondigestible carbohydrates colorectal cancer calprotectin Wnt signaling epigenetics
2018/11/12
Background: Hyperactive Wnt signaling is frequently observed in colorectal cancer. Higher intakes of dietary fiber [nondigestible carbohydrates (NDCs)] and the fermentation product butyrate are protec...
Targeted delivery of short-chain fatty acids to the human large bowel
Targeted delivery short-chain fatty large bowel
2018/11/30
The cecum and colon are an integral, but somewhat neglected, part of the human digestive system. This digestion is affected not by human enzymes but by the microbiota that degrade undigested dietary c...