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Synthesis and antimicrobial activities of some new biheterocyclic compounds containing 1,2,4-triazol-3-one and 1,3,4-thiadiazole moieties
1,2,4-triazol-3-one 5-thioxo-1,2,4-triazole
2010/10/18
2-(4-Amino-3-(4-chlorophenyl)-5-oxo-4,5--dihydro-1H-1,2,4-triazol- 1-yl)-N'-[(2,6-dihalogenophenyl)-methylene]acetohydrazides (3a,b) was obtained via the formation of 2-(4-amino-3-(4-chlorophenyl)-5-o...
Synthesis and in vitro anti-Helicobacter pylori activity of 2-(substituted benzylthio)-5-(5-nitro-2- furyl)-1, 3, 4-thiadiazole derivatives
1,3,4-Thiadiazole nitrofuran anti-Helicobacter pylori activity
2010/4/8
Starting from (5-nitrofuran-2-yl)methylene diacetate, a new series of 2-[(substituted benzyl)thio]-5-(5-nitro-2-furyl)-1,3,4-thiadiazoles (6a-n) were synthesized and the structures of the compounds we...
Synthesis and Characterization of Novel Azole Heterocycles Based on 2,5-Disubstituted Thiadiazole
1,3,4-thidiazoles fused heterocyclic ring Schiff bases
2010/4/16
Starting from 2-amino-5-mercapto-1,3,4-thiadiazole (1), a variety of new 1,2,4-triazino[5,4-b][1,3,4] thiadiazole (3), pyrazole (4), [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazole (5), phthalazine-3,6-dion...
Synthesis and Characterization of New Triheterocyclic Compounds Consisting of 1,2,4-Triazol-3-one, 1,3,4-Thiadiazole and 1,3,4-Oxadiazole Rings
1,2,4-triazol-3-one 1,3,4-thiadiazole 1,3,4-oxadiazole thiosemicarbazide diazotation deamination
2010/4/20
A series of acetic acid derivatives (2a-c) was synthesized by the condensation of compounds 1a-c with chloroacetic acid. The treatment of carboxylic acid derivatives with thiosemicarbazide in phospho...
Synthesis and Antinociceptive Activity of 2-[(2-Oxobenzothiazolin-3-yl)methyl]- 5-aminoalkyl/aryl-1,3,4-thiadiazole
2-Oxobenzothiazoline 1,3,4-thiadiazole antinociceptive activity
2010/4/20
Ten 2-[(2-oxobenzothiazolin-3-yl)methyl]-5-aminoalkyl/aryl-1,3,4-thiadiazole derivatives were synthesized. The chemical structures of these compounds were elucidated by their FT-IR and 1H-NMR spectral...
Synthesis and Antimicrobial Activity of Some Pyridyl and Naphthyl Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives
Synthesis Antimicrobial Activity 1,2,4-Triazole 1,3,4-Thiadiazole
2010/4/21
Synthesis of new 1,2,4-tri and 1,3,4-thiadiazoles, bearing isomeric pyridyl and 1-naphthyl is reported using 1,4-disubstituted thiosemicarbazides in alkaline and acidic media, respectively. The methyl...
Synthesis of Some New Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole and Their Derivatives
1,2,4-Triazole 1,3,4-Thiadiazole Derivatives
2010/4/21
Several 5-(isomeric pyridyl)-4-aryl-1,2,4-triazole-3-thiol/yl-thiomethyl/yl-thioethyl/yl-thiobenzyl and yl-thioglycolic acids were prepared as possible biologically active agents. The infrared, nuclea...