搜索结果: 1-15 共查到“生物学 CHIP”相关记录20条 . 查询时间(0.109 秒)
中国科学院上海营养与健康研究所邵振研究组建立用于多样本ChIP-seq数据分组定量比较的MAnorm2计算模型（图）
邵振 多样本ChIP-seq 数据分组 定量比较 MAnorm2 计算模型
2020/12/2
2020年11月19日，Genome Research在线发表了中国科学院上海营养与健康研究所中科院计算生物学重点实验室（马普伙伴计算生物学研究所）邵振课题组的方法学论文“MAnorm2 for quantitatively comparing groups of ChIP-seq samples”，报道了其开发的新一代MAnorm2计算模型。该模型能够对多样本ChIP/ATAC-seq数据按照特...
近日，国际著名学术期刊Lab on a Chip（中科院一区TOP类）以封面（Back Cover）形式刊载了中国科学院沈阳自动化研究所微纳米课题组在生物细胞操控与三维组装领域的最新研究成果Biomimetic construction of peritoneum to imitate peritoneal metastasis using digital micromirror device-b...
Blinking eye-on-a-chip used for disease modeling and drug testing（图）
eye-on-a-chip disease modeling drug testing
2019/10/21
People who spend eight or more hours a day staring at a computer screen may notice their eyes becoming tired or dry, and, if those conditions are severe enough, they may eventually develop dry eye dis...
Novel Chip-Based Gene Expression Tool Analyzes RNA Quickly And Accurately（图）
Novel Chip Gene Expression Tool Analyzes RNA Quickly And Accurately
2018/2/1
A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from a cancerous tissue sampl...
Bioreactors on a chip renew promises for algal biofuels（图）
Bioreactors chip renew promises algal biofuels
2017/10/25
For over a decade, companies have promised a future of renewable fuel from algae. Investors interested in moving the world away from fossil fuel have contributed hundreds of millions of dollars to the...
Organ-on-a-chip mimics heart’s biomechanical properties
Organ-on-a-chip mimics heart biomechanical properties
2017/3/14
The human heart beats more than 2.5 billion times in an average lifetime. Now scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing bi...
Chip-based technology enables reliable direct detection of Ebola virus
Chip-based technology detection of Ebola virus
2015/10/13
A team led by researchers at UC Santa Cruz has developed chip-based technology for reliable detection of Ebola virus and other viral pathogens. The system uses direct optical detection of viral molecu...
近日，华南师范大学生物光子学研究院2013级博士研究生舒博文同学在微纳流控领域顶级期刊 Lab on a Chip上发表了原创性研究论文“A handheld flow genetic analysis system (FGAS): towards rapid, sensitive, quantitative and multiplex molecular diagnosis at the poi...
Influence of Yeast Fermented Cassava Chip Protein (YEFECAP) and Roughage to Concentrate Ratio on Ruminal Fermentation and Microorganisms Using In vitro Gas Production Technique
Protein Source Rumen Fermentation In vitro Gas Production Rice Straw
2016/5/16
The objective of this study was to determine the effects of protein sources and roughage (R) to concentrate (C) ratio on in vitro fermentation parameters using a gas production technique. The experime...
Effect of Ground Corn Cob Replacement for Cassava Chip on Feed Intake, Rumen Fermentation and Urinary Derivatives in Swamp Buffaloes
Corn Cob Cassava Chip Rumen Ecology Purine Derivatives Swamp Buffalo Rice Straw
2016/5/10
Four Thai - rumen fistulated male swamp buffaloes (Bubalus bubalis), about four years old with 400±20 kg liveweight, were randomly assigned according to a 4×4 Latin square design to receive dietary tr...
ChIP-Seq是在全基因组水平上研究活体细胞中蛋白质和DNA相互作用谱的有效手段. 近年来, 随着高通量短序列DNA测序技术的快速发展, 研究基于新一代DNA测序方法的ChIP-Seq分析算法已经成为热点之一. 然而, 目前报道的分析方法主要是基于对免疫共沉淀获得的DNA片段进行片段大小选择后的ChIP-Seq数据, 也就是主要针对Solexa系统获得的数据进行分析的算法. SOLiD系统是目前...
活细胞依赖其众多的转录调控模块来实现复杂的生物功能，识别转录调控模块对深入理解细胞的功能及其转录机制有着重要的意义。本文结合酵母基因表达数据和ChIP-chip数据，提出了一种转录调控模块识别算法。该算法通过采用不同的P值阈值分别得到了核心集和粗糙集，然后对核心集和粗糙集进行判别，最后对基因进行扩展之后得到基因转录调控模块。将该算法运用到两个酵母基因表达数据中，得到了一些具有显著生物学意义的基因转...
摘要
提出了一种新的DNA芯片的封闭方法：1-碘丙烷封闭方法,并对1-碘丙烷和琥珀酸酐两种不同的封闭方法的封闭效果进行了比较实验，研究封闭试剂、封闭时间对氨基DNA芯片杂交结果所产生的影响。结果表明： 1-碘丙烷封闭效果明显好于琥珀酸酐的封闭效果，用1-碘丙烷封闭后的芯片进行杂交，芯片杂交信号强、背景噪声低，灵敏度高，整个封闭过程实验操作简单，时间短，1h即可达到所需效果。1-碘丙烷可以作为一种...
用整合微流控芯片系统分析黄山松RAPD片段多态性Analysis of Polymorphic RAPD Fragments in P.Taiwanensis Hayata Using an Integrated Microflluidic Chip-based System
整合微流控芯片系统 随机扩增多态DNA（RAPD） 黄山松
2007/12/31
摘要随机扩增多态DNA（randomly amplified polymorphic DNA，RAPD）标记可快速提供连锁信息，特别是在针叶树单倍体的大配子体中RAPD基因型也能得以确定［3］。在对多态性的RAPD片段进行分析时，传统的平板凝胶电泳分析法因人工操作，其有效的鉴别受到一定程度的限制，只能得到一些有关RAPD片段半定量信息。我们将整合微流控芯片系统作为一种新的工具运用于黄山松的多态性R...
Hsp/Hsc70相互作用蛋白CHIP在大鼠肾纤维化组织中的高表达
CHIP 表达 肾纤维化
2007/12/20
摘要 利用DNA重组技术 ,将编码人Hsp Hsc70相互作用蛋白CHIP(carboxylterminusofHsc 70 interactingprotein ,CHIP)全长、N端TPR及C端U box结构域的DNA片段分别构建于融合表达质粒pGEX 5X 1中 ,转化大肠杆菌 .纯化GST CHIP融合蛋白 ,制备了特异性识别人、小鼠及大鼠组织细胞内CHIP蛋白的多克隆抗体 .利用该抗体...