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中国科学院动物研究所专利：MONOCLONAL ANTIBODY AGAINST HUMAN PRPC AND USE THEREOF
中国科学院动物研究所 专利 人PrPC蛋白 单克隆抗体
2024/5/31
一种抗人PrPC蛋白的单克隆抗体，能够以靶向方式降低转录因子Twist1的表达水平，并诱导巨噬细胞和NK细胞靶向直肠癌肿瘤细胞。 抗体与西妥昔单抗联合用药的抑瘤效果也优于单用抗体或西妥昔单抗。
中国科学院动物研究所专利：Delayed senescence, malignant conversion of human mesenchymal stem cells can be a resistor, its preparation and use
中国科学院动物研究所 专利 人骨髓间 充质干细胞
2024/5/30
延缓衰老，制备恶性人骨髓间充质干细胞的方法可抗选择性。 制备方法， 第二密码子的253个氨基酸残基的FOXO3蛋白， 丝氨酸密码子编码丙氨酸突变的密码子，FOXO3蛋白密码子的第315位氨基酸残基，丝氨酸密码子编码丙氨酸突变的密码子编码2个突变中的一个突变，编码多能干细胞的基因组包括该步骤。 制备的重组间充质干细胞，并进一步提供其在移植治疗中的用途。 [附图]
Engineers devise a way to selectively turn on RNA therapies in human cells（图）
人类细胞 RNA疗法 治疗性蛋白质 癌症治疗
2023/6/21
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences...
The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT's Whitehea...
2022年4月25日，浙江大学遗传学研究所管敏鑫教授课题组在国际权威学术期刊《人类分子遗传学》（Human Molecular Genetics）在线发表聋相关基因编辑结合干细胞技术的最新研究成果，该研究通过CRISPR/Cas9 基因编辑技术对线粒体修饰基因突变进行遗传矫正，在内耳毛细胞样细胞中实现听觉功能重塑，为耳聋的基因治疗带来“新的曙光”，是领域内的重要突破。
“We have been interested in the romantic life of the parasite Cryptosporidium for some time,” says Boris Striepen, a scientist in Penn’s School of Veterinary Medicine.
Only one human fat cell subtype responds to insulin stimulation
AdipoPLIN fat cells insulin diabetes
2021/8/11
It is well known that fat cells can influence our sensitivity to insulin. Now, researchers have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that ...
Drug-resistant bacteria found in the guts of lemurs who live around humans The more human interaction they had, the higher the proportion of resistant bugs
antibiotics resistance lemur gut microbiota
2021/8/10
Researchers have found evidence for antibiotic resistance in the gut microbiomes of lemurs living close to humans. The more human contact they have, the more antibiotic resistance there is. Even capti...
Researchers film human viruses in liquid droplets at near-atomic detail
human viruses AAV genome
2021/8/11
Researchers have used advanced electron microscopy (EM) technology to see how human viruses move in high resolution in a near-native environment. The visualization technique could lead to improved und...
南京农业大学动物科技学院孙少琛教授团队在《Human Reproduction Update》顶刊发表综述论文（图）
孙少琛 Human Reproduction Update 卵母细胞
2022/3/15
2021年7月8日，南京农业大学动物科技学院孙少琛教授团队在生殖生物学科顶级学术期刊《Human Reproduction Update》（5年影响因子18.96，学科排名1/83）在线发表了题为The multiple roles of RAB GTPases in female and male meiosis的综述论文，全面概括和阐述了小G蛋白（单体GTP酶）RAB家族对卵母细胞成熟以及精子...
Every time we reach for a cup, our brains must assess our hands’ current position in relation to the mug and then command muscles to make the proper adjustments to successfully grab the handle.
Researchers look for human disease solutions in opossums（图）
human disease solutions opossums
2021/4/9
Scientists have examined the immune system of an unusual group of mammals, which includes a small South American opossum, to find solutions that evolution has produced to fight disease-causing pathoge...
Warm oceans helped first human migration from Asia to North America（图）
Warm oceans first human migration Asia to North America
2020/12/31
New research reveals significant changes in the circulation of the North Pacific Ocean and their impact on the initial migration of humans from Asia to North America.The U.S. National Science Fou...
Research on Tasmanian devil offers new insights into tackling human cancer（图）
Tasmanian devil human cancer
2020/8/14
A rare, transmissible tumor has brought the iconic Tasmanian devil to the brink of extinction, but new research by scientists at Washington State University and the Fred Hutchinson Cancer Re...
北京大学心理学院韩世辉课题组在Nature Human Behaviour发文揭示人类面孔种族分类加工的神经机理及其与面孔再认和利他意向的关系（图）
北京大学心理学院 韩世辉 Nature Human Behaviour 人类面孔种族 神经机理 关系
2019/10/31
把不同的个体归类为同一个种族，以此为基础在态度和行为上区别对待他族和本族成员，这种现象在人类社会广泛存在并产生严重后果，因此受到心理学、神经科学等多个领域的高度关注。北京大学心理与认知科学学院及麦戈文脑研究所韩世辉教授课题组率先使用脑成像技术，揭示了痛觉共情活动的种族偏好（Xu et al., 2009， Journal of Neuroscience ），并基于系统研究结果发表了“非对称种族加工...