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Glassfrogs Show Surprising Diversity of Parental Strategies
Glassfrogs Diversity Parental Strategies
2017/4/27
Laid on leaves hanging over streams in tropical rainforests, glassfrog eggs are tasty snacks for snakes, insects and other predators until they hatch and drop into the streams to begin life as tadpole...
2017 Keystone Symposia on Omics Strategies to Study the Proteome
Proteome Omics Strategies
2017/1/17
The meeting will begin on Sunday, January 29 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 2 with a closing plenary se...
Cellular strategies of protein quality control
Cellular strategies protein quality control
2015/12/11
Eukaryotic cells must contend with a continuous stream of misfolded proteins that compromise the cellular protein homeostasis balance and jeopardize cell viability. An elaborate network of molecular c...
Obstacles and Circumvention Strategies for Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus Vectors
gene therapy hematopoietic stem cells sickle cell disease
2015/5/21
High-efficiency transduction of hematopoietic stem cells (HSCs) by recombinant adeno-associated virus serotype 2 (AAV2) vectors is limited by (i) inadequate expression of cellular receptor/co-receptor...
Novel anaerobic bioremediation strategies for organic and metal contaminants
Bioremediation sediments microorganism biological transformation of pollutants metallic organic compounds
2015/1/28
Bioremediation is becoming a widely accepted solution for cleaning up contaminated sediment, water, and soil. The associated microbial, chemical, and geologic principles are still in their relative in...
Strategies for differentiation, identification and typing of medically important species of mycobacteria by molecular methods
human bovine and avian tuberculosis
2015/1/20
Molecular biology methods offer new opportunities to differentiate, identify and type bacterial species and strains. These methods use the variability of nucleic sequences of genes such as 16S rDNA, b...
NOVEL STRATEGIES TO MODULATE SYNAPTIC COMMUNICATION AND INVESTIGATE THE ROLE OF HDAC6 IN ALZHEIMER’S DISEASE
Photochemistry GABA_A receptors Alzheimer's disease Tau HDAC6
2014/12/10
Neuronal communication is mediated by chemical signaling at the synapse. The underlying molecular mechanisms of learning and memory are poorly understood. Very few tools are available to study how mem...
MASS SPECTROMETRY BASED EXPERIMENTAL STRATEGIES TO CHARACTERIZE NATIVE AND NON-NATIVE DISULFIDE BONDS IN CYSTEINE-RICH PROTEIN THERAPEUTICS
Mass spectrometry disulfide scrambling protein therapeutics disulfide-bond characterization
2014/12/10
The impact post-translational modifications (PTMs) can have on the structure, function, and immunogenicity of protein therapeutics makes it especially important for these protein-based treatments to b...
Molecular farming: strategies, expression systems and bio-safety considerations
biopharmaceuticals recombinant proteins rhizosecretion therapeutics transformation
2014/3/31
Molecular farming is an experimental application of biotechnology that involves the genetic modification of crops for the production of proteins and chemicals for medicinal and commercial purposes. Th...
Comparing the efficiency of sampling strategies to establish a representative in the phenotypic-based genetic diversity core collection of orchardgrass (Dactylis glomerata L.)
core collection genetic diversity germplasm collection orchardgrass phenotypic variation representativeness sampling strategies
2014/2/24
Establishing a core collection that represents the genetic diversity of the entire collection with a minimum loss of its original diversity and minimal redundancies is an important problem for gene ba...
Evolution of optimal Levy-flight strategies in human mental searches
Evolution of optimal Levy-flight strategies human mental searches Computer Science and Game Theory
2012/4/20
Recent analysis of empirical data [F. Radicchi, A. Baronchelli & L.A.N. Amaral. PloS ONE {\bf 7}, e029910 (2012)] showed that humans adopt L\'evy flight strategies when exploring the bid space in on-l...
HIV-1 NEF: THERAPEUTIC STRATEGIES AND VIROLOGICAL SYNAPSE-MEDIATED INFECTION
THERAPEUTIC STRATEGIES VIROLOGICAL SYNAPSE-MEDIAT
2015/5/21
HIV-1 infection is one of the greatest public health concerns today. The current HIV/AIDS therapy is effective in halting virus multiplication and has improved the outlook of AIDS; however, high cost,...
Use of murine models to test novel gene transfer strategies for the treatment of Fanconi anemia
Gene therapy mobilization hematopoiesis
2015/5/21
he dawn of the genetic era has allowed for investigation of gene transfer therapy as a treatment for certain diseases. Fanconi anemia (FA) is a rare genetic disorder in which the majority of patients ...
Development of an Integrated General Model (IGM) System for Comparison of Genetic Gains from Different Bull Selection Strategies for Korean Brown Cattle (Hanwoo)
Breeding Scheme Hanwoo Integrated General Simulation Model Simulation
2016/5/9
To advance the effectiveness of the current Hanwoo improvement system, we developed a general simulation that compared a series of breeding schemes under realistic user circumstances. We call this sys...
Structures and Assumptions: Strategies to Harness Gene $\times$ Gene and Gene $\times$ Environment Interactions in GWAS
Structures Assumptions Strategies Harness Gene $\times$ Gene Gene $\times$ Environment Interactions in GWAS
2010/11/16
Genome-wide association studies, in which as many as a million single nucleotide polymorphisms (SNP) are measured on several thousand samples, are quickly becoming a common type of study for identify...