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Association of Cardiorespiratory Fitness with Elevated Hepatic Enzyme and Liver Fat in Japanese Patients with Impaired Glucose Tolerance and Type 2 Diabetes Mellitus
Cardiorespiratory fitness hepatic enzyme non-alcoholic fatty liver abdominal obesity insulin resistance
2015/5/5
No study has so far determined whether a favorable level of cardiorespiratory fitness (CF) contributes to a reduced risk of elevated hepatic enzymes and a high degree of liver fat in patients having v...
Bronchodilator Efficacy of Single Doses of Indacaterol in Japanese Patients with COPD: A Randomised, Double-Blind, Placebo-Controlled Trial
beta2-agonists bronchodilator COPD efficacy indacaterol
2010/11/12
In the Japanese COPD population studied, single doses of indacaterol (150, 300, and 600μg) provided sustained 24-h bronchodilation, with onset of action within 5 min post-dose. All doses were well tol...
One Year Treatment with Omalizumab Is Effective and Well Tolerated in Japanese Patients with Moderate-to-Severe Persistent Asthma
asthma efficacy Japanese omalizumab safety evaluation
2010/11/12
Treatment with omalizumab significantly improved lung function. A subgroup of patients with inadequately controlled severe persistent asthma, despite high dose inhaled corticosteroids and other multip...
Comparison of the Asthma Health Questionnaire-33-Japan and the Short-Form 36-Item Health Survey for Measuring Quality of Life in Japanese Patients with Asthma
asthma Asthma Health Questionnaire (AHQ)-Japan Japanese quality of life questionnaire
2010/11/17
Our results show that the AHQ-33 is useful as a disease-specific QOL instrument in Japanese patients with asthma and that it is better than the SF-36, which is a generic QOL instrument. In the future,...
Therapeutic Effect of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, on Japanese Patients with Seasonal Allergic Rhinitis
cysteinyl leukotriene receptor dose-response relationship montelukast rhinitis allergic seasonal
2010/11/17
Background: Secretion of nasal discharge was enhanced and airway-resistance in the nasal cavity was augmented, resulting in nasal congestion, when leukotrienes were administered to the nasal mucosa. T...
Increased incidence of allergic disorders and elevated food-specific serum IgG4 levels in Japanese patients with Crohn's disease
allergic disorder food allergy IgE IgG4 inflammatory bowel disease
2010/11/29
An allergic response to foreign intestinal antigens such as those contained in food has been implicated as a causative factor in the development of inflammatory bowel disease (IBD). In this study, we ...
The Clinical Evaluation of the Acceptance of Fluticasone Propionate Diskus® by Older Japanese Patients with Bronchial Asthma
asthma drug compliance Fluticasone propionate Diskus® older patients
2010/11/22
The mean required times (seconds) were significantly different between patients aged 75 years or older, and with patients less than 65 years of age; 45.8 ± 8.1 vs. 31.8 ± 12.3 (p = 0.046) in the BDP g...