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Sho-seiryu-to Suppresses Histamine Signaling at the Transcriptional Level in TDI-Sensitized Nasal Allergy Model Rats
allergy gene expression histamine H1 receptors histamine signaling histidine decarboxylase Th2 cytokines
2010/11/16
SST significantly suppressed TDI-induced nasal allergy-like symptoms. TDI provocation showed a significant up-regulation of histamine H1 receptor (H1R) and histidine decarboxylase (HDC) gene expressio...
Dendritic Cells—Importance in Allergy—
asthma atopic dermatitis contact dermatitis Th1/Th2
2010/11/18
In this review we discuss the role of dendritic cells (DC) in the pathogenesis of allergic contact hypersensitivity (ACH) and atopic disorders, such as asthma and atopic eczema. In ACH patients, DC re...
Translation of the human genome into clinical allergy, part 2
basophils mast cells microarray system biology transcriptome
2010/11/22
After completion of sequencing of the human genome, you will no longer be able to discover a new gene and may not be able to find a new molecule in the human body. Instead, you may find many new molec...