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Rat reproductive tissues contained both 15-hydroxy-prostaglandin dehydrogenase (PGDH) and delta 13-reductase activities, while rabbit tissues exhibited only PGDH activity. In the rat, delta 13-reduc...
In order to examine the possible role of androgens in the isotonic response of the isolated rat aorta, a highly active mimic of thromboxane was employed. The maximum response to this TXA2-mimic U4...
Ejaculates from normal and castrated bulls were evaluated for the presence of inhibin-like activity. Inhibin activity found in the seminal plasma of normal bulls became undetectable after castrati...
The purpose of this study was to investigate the in vivo effects of intracavernosal injections of adrenomedullin (ADM), calcitonin gene-related peptide (CGRP), nociceptin, vasoactive intestinal po...
After castration the rat ventral prostate undergoes regression. This process occurs due to the induction of apoptosis, or active cell death, in the epithelial cells of the gland. Several genes, incl...
Inhibin has been suggested to play a role in gonadal feedback regulation of follicle-stimulating hormone (FSH) secretion; however, neither the half-life nor the time course of action of recombinan...
The endocrine mechanisms underlying the response to unilateral castration were examined by determining systemic androgen and luteinizing hormone (LH) concentrations, as well as testicular vein andro...
It is known that abnormal androgen dynamics in the tissues is a cause of androgen-dependent disorders. Investigation of tissue androgen levels could provide a clue to the elucidation of disorders....
Prostate cancer is the most frequently diagnosed cancer and the second cause of cancer death in men in North America (Jemal et al, 2003). In fact, one of eight men will be diagnosed with prostate canc...
The goal of this study was to investigate the effects of medical castration (luteinizing hormone-receptor hormone [LH-RH] agonist treatment) or surgical castration on erectile function in an animal ...

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