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Previous results, simultaneously confirmed by others, suggest that a relationship exists between sperm acrosin levels and fertility in man. The assessment of sperm acrosin may therefore be a useful ...
This study compared the cryoprotective effect of glycerol with that of a zwitter ion buffer system (TESTCY). Spermatozoa that are cryopreserved in the presence of glycerol possess a somewhat highe...
Acrosin is a sperm serine proteinase whose activity appears to be essential for fertilization in mammals, although this has not been shown in man due to experimental limitations. The present stu...
Glycosaminoglycans obtained from shark cartilage, whale cartilage, porcine intestinal mucosa, porcine skin, and human umbilical cord were found to accelerate the in vitro conversion of highly puri...
Ten different methods were evaluated to determine the treatment for obtaining maximal amounts of acrosin, proacrosin, and acrosin inhibitor (the acrosin system) from human spermatozoa by a single te...
The aim of this study was to investigate whether the molecular abnormality of proacrosin is associated with an unexplained failure of in vitro fertilization (IVF) and low acrosin activity in human...
Mammalian proacrosin gene expression was considered to be exclusively postmeiotic until recent studies detected the presence of proacrosin mRNA in mouse pachytene spermatocytes. To determine if rat ...
Acrosin, an acrosomal serine protease, is believed to have a role in fertilization. The enzyme is synthesized in an enzymatically inactive precursor form, proacrosin, and is processed to enzymatical...
The authors studied the interaction of calmodulin (CaM) with proacrosin and acrosin from ram spermatozoa. CaM binding evaluated by the [125I]-CaM overlay procedure was shown to occur preferentially ...
Mammalian sperm must undergo capacitation, a preparation period in the female reproductive tract or in vitro, in order to fertilize. We have previously described a Mr 32 000 tyrosine phosphorylated ...

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