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Background: Clinically significant premenstrual syndrome (PMS) affects 15–20% of premenopausal women, substantially reducing quality of life. Women with PMS often are counseled to minimize caffeine in...
Elevated concentrations of plasma total homocysteine (tHcy) and serum total cholesterol are risk factors for ischemic heart disease (IHD). Previous studies showed that the consumption of very high ...
In population studies, high intakes of coffee are associated with raised concentrations of plasma homocysteine, a predictor of risk of cardiovascular disease. Chlorogenic acid is a major polyphenol...
Elevated blood concentrations of total homocysteine (tHcy) have been implicated in the pathogenesis of atherosclerotic cardiovascular disease. Previous studies identified suboptimal nutritional sta...
Approximately 40,000 women in the U.S. are diagnosed with endometrial cancer annually. Biological data suggest coffee or tea consumption may lower endometrial cancer risk through estrogenic and insuli...
Cutaneous melanoma accounts for less than 5% of all skin cancers but over 75% of skin cancer related deaths. Prior biologic research suggests caffeine may arrest cancer cell formation and metastasis i...
Lung cancer has been the leading cause of cancer death in women for the past three decades. Although smoking is the most important risk factor for lung cancer, not all lung cancer deaths in American...
Background: The long-term longitudinal evidence for a relation between coffee intake and hypertension is relatively scarce.Objective: The objective was to assess whether coffee intake is associated wi...
Coffee oil potently raises serum cholesterol levels in humans. The diterpenes cafestol and kahweol are responsible for this elevation. Coffee oil also causes elevation of liver enzyme levels in serum....
Humans and animals show a certain consistency in the response of their serum lipids to fat-modified diets. This may indicate a genetic basis underlying this response. Coffee oil might be used as a mod...
Accumulating evidence suggests that certain dietary polyphenols have biological effects in the small intestine that alter the pattern of glucose uptake. Their effects, however, on glucose tolerance in...
Background: A high plasma total homocysteine concentration is associated with increased risk of cardiovascular disease. Consumption of unfiltered or filtered coffee raises total homocysteine conc...

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