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Estimate of maximum expiratory flow based on the equal pressure point concept and Weibel's lung model
human Weibel's lung model Maximal Expiratory Flow Rate
2009/7/20
Estimate of maximum expiratory flow based on the equal pressure point concept and Weibel's lung model.
Respiratory gas exchange and lung perfusion in man during and after head-out water immersion
CO2 carbon dioxide carbon monoxide pulmonary human CO
2009/7/20
The respiratory gas exchange for O2, CO2, and CO has been studied in nine healthy male subjects before, during, and after head-out water immersion. Distribution of lung perfusion and ventilation were ...
Blood-brain and blood-lung barrier alteration by dysbaric exposure
decompression blood-lung exposure
2009/7/20
Failure of certain circulating substances to penetrate specific organs led to the concept of blood-organ barriers. Such barriers can be altered by various physical or chemical means. This report conce...
Influence of hydrostatic compression of the chest and intrathoracic blood pooling on static lung mechanics during head-out immersion
human immersion intrathoracic blood pooling respiratory
2009/7/20
The effect of water immersion on static lung volumes and pressure-volume curves was studied in five subjects. A special container allowed measurements during nonimmersion, head-out immersion, and thor...
Effects of immersion and static lung loading on submerged exercise at depth
CO2 carbon dioxide human exercise immersion
2009/7/17
The effects of static lung loading in the range +20 cmH2O to -20 cmH2O was investigated in 3 male subjects breathing air during submerged exercise in the prone position at pressures ranging from 1.45 ...
Effects of hyperbaric oxygen on heart,brain,and lung functions in rat
hyperbaric rat heart brain lung oxygen pressures
2009/7/16
Electrocardiogram (ECG), electrocorticogram (ECoG), and respiratory rate (RR) were monitored in awake, unrestrained rats during continuous exposure to 1, 3, and 5 ATA O2 until death. The RR showed a c...
Mechanical and physical factors in lung function during work in dense environments
hypoventilation pulmonary human
2009/7/15
The major effects of breathing dense gas during physical exercise in hyperbaric environments can be traced to high airway resistance during inspiration and expiration and especially to an increased te...
Quantitative ultrastructural study of the rabbit lung: exposure to 60% oxygen for 21 days
pulmonary oxygen toxicity animal rabbit
2009/7/9
When rabbits were exposed to 60% oxygen for 21 days, arterial PaO2 showed statistically insignificant changes at 6-8 days (69 +/- 5 Torr) and 14-16 days (62 +/- 5 Torr); at 21 days the PaO2 was signif...
Static lung load and posture effects on pulmonary mechanics and comfort in underwater exercise
exercise pulmonary work of breathing position immersion
2009/7/8
Static lung load (SLL), or transrespiratory pressure gradient, imposed by underwater breathing apparatus can affect breathing comfort and mechanics, especially during exertion. We examined the effects...
Probable lung injury by long-term exposure to oxygen close to 50 kilopascals
saturation decompression oxygen toxicity pulmonary
2009/6/12
To investigate the possibility of lung injury after long-term saturation dives where oxygen partial pressure was kept between 42 and 50 kPa, we measured lung volumes, diffusing capacity (DLCO/VA), and...
Dibutyryl cAMP effects on thromboxane and leukotriene production in decompression-induced lung injury
decompression neutrophil lung injury
2009/6/8
Decompression-induced venous bubble formation has been linked to increased neutrophil counts, endothelial cell injury,release of vasoactive eicosanoids, and increased vascular membrane permeability.
Glutathione in the cellular defense of human lung cells exposed to hyperoxia and high pressure
human oxygen toxicity high pressure
2009/6/8
Saturation diving involves exposure to elevated partial pressure of oxygen (Po2) and high pressure. The present work demonstrated that hyperoxic exposure for up to 72 h had significant effects on huma...
Effect of anti-C5a antibody on blood-lung and blood-brain barrier in rabbits after decompression
decompression pulmonary complement rabbit animal
2009/6/8
The complement activation product C5a may be an important mediator of tissue injury after decompression stress. This study investigated whether the administration of anti-C5a antibody may reduce chang...
Increased lung compliance in response to a moderate hyperoxic exposure
oxygen toxicity saturation decompression pulmonary respiratory
2009/6/5
With deep saturation diving a reduction in vital capacity caused by oxygen toxicity may be opposed by a training effect of respiratory muscles due to increased gas density and work of breathing. We me...
Smoke inhalation-induced alveolar lung injury is inhibited by hyperbaric oxygen
neutrophil pulmonary hyperbaric Smoke inhalation alveolar lung injury
2009/6/5
Smoke-induced lung injury in rats was assessed in terms of histopathology, gross mortality, neutrophil accumulation and as capillary leak. Administration of hyperbaric oxygen (HBO2), 2.8 atm abs for 4...