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Pharmacokinetics of 7 alpha-methyl-19-nortestosterone in men and cynomolgus monkeys
MCR SHBG replacement therapy male
2009/2/17
Testosterone and its esters are widely used for androgen replacement therapy. In the prostate, testosterone ins 5 alpha-reduced to dihydrotestosterone (DHT), which leads to an amplification of its...
The antigonadotropic action of testosterone but not 7alpha-methyl-19-nortestosterone is attenuated through the 5alpha-reductase pathway in the castrated male rat pituitary gland
antigonadotropic action testosterone 7alpha-methyl-19-nortestosterone 5alpha-reductase castrated male rat pituitary gland
2008/12/25
The enzyme 5alpha-reductase plays a significant role in the prostate to amplify the action of testosterone (T) by converting it to a more potent androgen, dihydrotestosterone (DHT). The role of 5alp...
Testicular Expression of Steroidogenic Enzyme Genes Is Related to a Transient Increase in Serum 19-nortestosterone during Neonatal Development in Pigs
Cytochrome P450 Aromatase Pig Testis 19-Nortestosterone
2016/4/27
Cytochrome P450 aromatase is responsible for the biosynthesis of estrogen. It is also responsible for the endogenous production of 19-nortestosterone (nandrolone), an anabolic androgen unique to pigs....