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Peripheral neuropathy risk and a transcobalamin polymorphism: connecting the dots between excessive folate intake and disease susceptibility
Peripheral neuropathy risk a transcobalamin polymorphism dot disease susceptibility
2018/12/19
Advances in the broad field of nutritional genomics continue to shed light on variable disease susceptibility to modifications in micronutrient intake within populations. This is certainly the case wi...
Transcobalamin 776C→G polymorphism is associated with peripheral neuropathy in elderly individuals with high folate intake
folate folic acid peripheral neuropathy TCN2 776C>G polymorphism transcobalamin vitamin B-12
2018/12/19
Background: The 776C→G polymorphism of the vitamin B-12 transport protein transcobalamin gene (TCN2) (rs1801198; Pro259Arg) is associated with a lower holotranscobalamin concentration in plasma. This ...
The important study by Brito et al. (1) suggests that a single high dose of vitamin B-12 can improve peripheral sensory nerve function in asymptomatic elderly subjects with vitamin B-12 deficiency and...
Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B
Clevudine Telbivudine Mitochondrial toxicity Pegylated interferon
2011/4/2
The development of clevudine as a treatment for hepatitis B was terminated recently because of case reports of myopathy.
In each case, the onset of symptoms occurred between 8 and 13 months after the...
Chronic oral Silybum Marianum aqueous extract attenuates streptozotocin-diabetic neuropathy
Silybum marianum Nerve function Diabetic neuropathy Oxidative stress
2009/11/26
Background: Oxidative stress is implicated as a final common pathway in the development of diabetic neuropathy and pharmacological interventions targeted at inhibiting free radical production have sho...
Acute Motor Axonal Neuropathy Developing During Helicobacter pylori Infection
Guillain-BarrŽ Syndrome (GBS) neuropathy Antibody
2009/6/23
Guillain-BarrŽ Syndrome (GBS) is an acute demyelinating neuropathy of immunological origin caused by antibodies formed against nerve antigens. GBS has an acute onset and its incidence in children...
Hyperbaric oxygen therapy in two patients with non-arteritic anterior optic neuropathy who did not respond to prednisone
Anti-Inflammatory Agents Constriction human Hyperbaric Oxygenation Middle Aged
2009/6/5
Recent advances in understanding the effects of hyperbaric oxygen (HBO) on retinal anoxia gave rise to new interest in the possibility of using it as therapeutic treatment for ischemic conditions of t...
Evaluation of diabetic neuropathy using the tone-entropy analysis, a noninvasive method to estimate the autonomic nervous function
tone-entropy analysis noninvasive method autonomic nervous function
2009/5/8
It is clinically important to diagnose diabetic neuropathy at the early stage. In this study, the toneentropy analysis of electrocardiogram was applied to diabetic patients to evaluate its usability...
Treatment of Radiation - Induced Optic Neuropathy in the Pediatric Population: A Case Report and Review of the Literature
Radiation Optic Neuropathy Pediatric case report
2009/5/8
Fontanesi J, Golden EB, Cianci PC, Heideman RL. Treatment of Radiation - Induced Optic Neuropathy in the Pediatric Population: A Case Report and Review of the Literature. J. Hyperbaric Med 1991; 6(4)...
Identifying diabetic patients with cardiac autonomic neuropathy by heart rate complexity analysis
diabetic patients cardiac autonomic neuropathy heart rate
2010/2/25
Cardiac autonomic neuropathy (CAN) in diabetes has been called a "silent killer", because so few patients realize that they suffer from it, and yet its effect can be lethal. Early sub clinical detecti...
Leber遗传性视神经病变家系的线粒体基因突变分析Analysis of Mitochondrial Gene Mutations in Pedigrees of Leber′s Hereditary Optic Neuropathy
Leber遗传性视神经病 线粒体DNA 点突变
2007/12/30
摘要为探讨Leber遗传性视神经病变（Leber′s hereditary optic neuropathy，LHON）家系线粒体DNA（mtDNA）常见致病原发突变的频谱,用聚合酶链反应（polymerase chain reaction，PCR）和单链构象多态性（single-stranded conformational polymorphism，SSCP）以及DNA测序的方法，对13个家系...
Congenital Sensory Neuropathy as a Differential Diagnosis for Phagocytic Immunodeficiency
Congenital defect Hereditary Sensory and Autonomic Neuropathies
2010/2/3
There are few reports about congenital indifference to pain or Hereditary and Sensory Autonomic Neuropathy (HSAN). Several investigations for pathophysiology of this syndrome have been performed and d...