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Comparison of Topical Nifedipine With Oral Nifedipine for Treatment of Anal Fissure:A Randomized Controlled Trial
Fissure in Ano Nifedipine Sphincterotomy Endoscopic
2015/10/14
Background: Medical sphincterotomy has gained popularity as a treatment for anal fissure. Calcium channel blockers in topical forms could also be appropriate with low adverse effects.
Effects of formulation variables on Nifedipine microspheres prepared by solvent evaporation technique
Microspheres Solvent evaporation
2010/1/6
Preparation and characterization of nifedipine microspheres using ethylcellulose as matrix polymer is described. Nifedipine microspheres were prepared by solvent evaporation technique. The influence o...
Synthesis and Calcium channel antagonist activity of Nifedipine analogues with Chloroindolyl substituent
Synthesis Calcium channel antagonist activity Nifedipine analogues Chloroindolyl substituent
2010/1/6
Various diester analogues of nifedipine in which the ortho nitrophenyl group at position 4 were replaced by 3-chloro-1H-2-indolyl substituent, were synthesized and evaluated as calcium antagonists on ...
Nifedipine in the treatment of liver toxicity induced by Acetaminophen overdose in mice
Liver toxicity Nifedipine liver
2009/12/30
Acetaminophen is an analgesic and antipyretic drug, which is widely used by public and poisoning with this drug, is common. One of the most important adverse effects of acetaminophen poisoning is cent...
The Therapeutic Effect of Nifedipine as a Ca+2 Entry Blocker on Experimental Transient Ischemic Retina
Nifedipine Ischemia Retina VSCC Blocker
2009/6/30
We evaluated the effect of nifedip-ine, an L-type voltage sensitive Ca+2 channel (VSCC) blocker, on the onset of neuronal damage induced by transient ischemia of guinea pig retinas in vivo. The animal...
A Comparison of the Effectiveness of Sublingual Losartan,Sublingual Captopril and Sublingual Nifedipine in Hypertensive Urgency
Hypertensive Urgency,Losartan
2009/6/30
The use of sublingual captopril and nifedipine has been indicated in hypertensive emergencies and in patients with essential hypertension, with the assumption that by this route, there would be a fast...
Glycosaminoglycans in Enlarged Gingiva Induced by Nifedipine
drug-induced enlarged gingiva nifedipine glycosaminoglycans hyaluronic acid
2009/5/20
Gingival overgrowth is a common side effect associated with calcium channel blockers. We analyzed glycosaminoglycans (GAG) content in gingiva enlarged by nifedipine.
Gingival GAG were extracted from ...
A case report of Choronic Periodontitis with Gingival Overgrowth Induced by Nifedipine
hypertension nifedipine gingival Overgrowth initial preparation
2009/5/15
This paper reports a case of nifedipine-induced gingival overgrowth that was successfully treated by initial preparation without surgical therapy. A 54-year-old man visited our clinic with the chief c...
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR DETERMINATION OF NIFEDIPINE IN HUMAN PLASMA
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD NIFEDIPINE HUMAN PLASMA
2010/4/29
A relatively simple normal phase high performance liquid chromatography (HPLC) method was modified for determination of nifedipine in human plasma. The method is based on ultraviolet detection at 235 ...