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Effect of epidural administration of lidocaine, fentanyl and their combination on the minimum alveolar concentration of halothane in dogs
intrathecal analgesia anaesthesia
2015/2/5
The efficacy of lidocaine, fentanyl, combination of both (2 mg/kg of lidocaine, along with fentanyl in the dose of 0.005 mg/kg) and saline (as a control) administered epidurally to 40 healthy dogs was...
Effect of introducing the mucosal atomization device for fentanyl use in out-of-hospital pediatric trauma patients
device Emergency Medical Services fentanyl intranasal pain assessment pediatric trauma
2014/11/28
Background: Pain associated with pediatric trauma is often under-assessed and undertreated in the out-of-hospital setting. Administering an opioid such as fentanyl via the intranasal route is a safe a...
Adverse Effects of Morphine and Fentanyl for Stomatitis in Patients Receiving Allogeneic Hematopoietic Cell Transplantation—A Single Center Retrospective Analysis
Stomatitis Morphine Fentanyl Allo-HCT Constipation
2013/1/30
Opioids are widely used as analgesics for oral mucositis in allogeneic hematopoietic cell transplantation (allo-HCT). Their main adverse events are nausea, vomiting, constipation, psychological sympto...
Comparison of Remifentanyl, Alfentanyl and Fentanyl Co-Administered with Propofol to Facilitate Laryngeal Mask Insertion
Remifentanil alfentanil fentanil propofol laryngeal mask airway
2010/2/24
Opiates co-administered with propofol improved the LMA insertion conditions compared to propofol alone. Out of the opiates, remifentanil had the highest success rate.
Small-Dose Fentanyl in Intravenous Versus Epidural Preemptive Analgesia
Analgesia preemptive Analgesics opioid fentanyl Surgery orthopedic
2009/6/30
In this randomized, double-blinded study, the preemptive effects of intravenous and epidural fentanyl analgesia were compared with post-incisional analgesia in 40 patients undergoing orthophedic surge...
本文对十一个4-取代Fentanyl类化合物进行了量子化学(INDO)计算, 研究了它们的电子结构及构效关系. 结果表明, 这些化合物同其他Fentanyl类化合物在主要活性部位和电子结构趋势上基本相同. 酰胺氧原子是最重要的负电中心, 哌啶氮原子在季铵化后发挥正电中心作用. 4-取代基的极性基团可能以电荷转移作用或氢键接受体形式与受体极性部位结合, 并能影响其他活性部位电子密度. 另外, 4-取...