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Decreased Activity in Neuropathic Pain Form and Gene Expression of Cyclin-Dependent Kinase5 and Glycogen Synthase Kinase-3 Beta in Soleus Muscle of Wistar Male Rats
Neuropathic Pain Soleus Muscle CDK5 Protein Kinase
2015/11/6
Background: The relationship between decreased activity/neuropathic pain and gene expression alterations in soleus muscle has remained elusive.
Glycogen is a major energy reserve in most eukaryotes and its rate of synthesis is controlled by glycogen synthase. The activity of eukaryotic glycogen synthase is regulated by the allosteric activato...
Motility potential of macaque epididymal sperm: the role of protein phosphatase and glycogen synthase kinase-3 activities
Monkey spermatozoa enzymes caput caudal
2009/2/18
Human and monkey ejaculated sperm contain protein phosphatase-1 (PP1), PP1 inhibitor 2 (12), and glycogen synthase kinase-3 (GSK-3). Inhibition of ejaculated human sperm protein phosphatase (PP) a...
Changes in Sperm Glycogen Synthase Kinase-3 Serine Phosphorylation and Activity Accompany Motility Initiation and Stimulation
Epididymis protein kinase B phosphoinositide 3-kinase
2008/12/22
Sperm motility is regulated by protein phosphorylation. We have shown that the signaling kinase, glycogen synthase kinase-3 (GSK-3), is present in spermatozoa. In somatic cells, GSK-3 is regulated b...
Evidence for a Role of Glycogen Synthase Kinase-3ß in Rodent Spermatogenesis
Testis meiosis tubule culture Rim11p
2008/12/19
Glycogen synthase kinase-3ß (GSK-3ß) regulates cell metabolism, cell cycle, and cell fate through the phosphorylation of a diverse array of substrates. Herein, we provide evidence that s...