搜索结果: 136-150 共查到“知识库 多肽与蛋白质生物化学”相关记录626条 . 查询时间(5.062 秒)
Understanding the allosteric mechanism of the Escherichia coli Hsp70 molecular chaperone, DnaK
Hsp70 Protein aggregation Enzyme Polypeptide Protein function Nucleotides. The ATP hydrolysis
2014/12/11
The Hsp70 family molecular chaperones prevent protein aggregation under heat shock conditions. They are highly conserved, and have a N-terminal ATPase domain, which binds and hydrolyzes ATP, and a C-t...
Microtubule dynamics and behavior during the assembly and disassembly of mammalian mitotic spindles
Mitosis cytoskeleton element movement protein cells genome microtubules biological polymer
2014/12/11
The mitotic apparatus is composed of a complex, seemingly chaotic, but wonderfully organized compilation of cytoskeletal elements and motor proteins. Its task is to assure that each daughter cell rece...
The HFD of Cse4p is sufficient for a functional centromere specific nucleosome: An investigation into kinetochore formation on cen DNA
Centromere chromosomes cell division protein chromosome axis of fiber
2014/12/11
Centromeres are the site on a chromosome that allows for proper chromosome segregation during cell division. The kinetochore, a DNA-protein complex that forms at the centromere, attaches the chromosom...
The influence of WC1 isoforms on gammadelta T cell function
Scavenger receptor WC1 molecules diversity rich cysteine membrane surface glycoprotein T cells
2014/12/11
WC1 molecules are an extensively diversified family of integral type 1 scavenger receptor cysteine rich (SRCR) membrane glycoproteins expressed on the surface of arteriodactyls such as sheep, cattle, ...
Functional analysis of Hic-5/ARA55 isoforms in C2C12 myogenesis
protein protein cell clones hydrogen peroxide androgen receptor activator
2014/12/11
Hic-5 is a focal adhesion protein of paxillin superfamily that was initially cloned from mouse osteoblasts as a TGF-β or H2O2 inducible cDNA. As well, Hic-5 was independently identified as an Androgen...
Investigations of glycoprotein co-translational maturation in the cell
New protein Protein Endoplasmic reticulum cavity Protein folding Coupling molecules Fold the sensor Membrane glycoprotein
2014/12/11
The earliest steps of nascent protein folding are critical to the overall folding efficiency. Folding events start as soon as the protein is translocated into the endoplasmic reticulum lumen, where th...
Changes in the mutual orientation of tRNA and 23S rRNA at the peptidyl transferase center of the ribosome detected by crosslinking of a photoreactive transition-state analog
Amino acids dynamic interaction ribosomes peptide bonds peptidyl transferase ribosomes
2014/12/11
Dynamic interactions between the amino acid acceptor end of tRNA and the ribosome underlie the synthesis of successive peptide bonds at the peptidyl transferase center (PTC) of the 50S ribosomal subun...
The role of the crumbs complex in vertebrate rod morphogenesis and its regulation by a novel FERM protein mosaic eyes
Zebrafish Mosaic eyes retinal texture protein complex crumbs protein cell polarity
2014/12/11
Mutations in zebrafish mosaic eyes result in the disrupted retina lamination and other abnormalities. The moe locus encodes a FERM protein. In this study I sought to determine in which molecular pathw...
A post-import pathway for protein targeting to chloroplast inner membrane
Chloroplast membrane metabolites photosynthesis lipid metabolism biogenesis membrane protein and chloroplast
2014/12/11
The chloroplast envelope plays critical roles in the synthesis and regulated transport of key metabolites, including intermediates in photosynthesis and lipid metabolism. Despite this importance, the ...
TRAF-interacting protein, an inhibitor of the canonical nuclear factor-kappaB pathway, plays a key role in the estradiol -dependent apoptosis of the dual-phenotype gamma amino butyric acid/glutamate neurons in the anteroventral periventricular nucleus of the male rat
Mediated estradiol LH surge neurons male AVPV E2 - mediated cell death neurons
2014/12/11
The anteroventral periventricular nucleus (AVPV) of the preoptic area mediates the positive feedback effects of estradiol (E2) on LH surge in rats. Consistent with their role in female reproduction, t...
Functional analysis of Moe (Epb4.1l5) in zebrafish development and the identification of novel Epb4.1l5 binding proteins
Zebrafish Protein Mammals Red blood cell protein Embryonic development. The texture of retina
2014/12/11
The zebrafish protein Mosaic eyes (Moe), and the mammalian orthologue Erythrocyte protein band 4.1-like 5 (Epb4.1l5), are FERM (for Protein 4.1, Ezrin, Radixin, Moesin) domain containing proteins that...
Determinants for Stop-Transfer and Post-Import Pathways for Protein Targeting to the Chloroplast Inner Envelope Membrane
chloroplast envelope inner envelope protein targeting
2014/12/11
Chloroplast biogenesis relies on the import of thousands of nuclear encoded proteins into the organelle and proper sorting to their sub-organellar compartment. The majority of nucleus-encoded chloropl...
Retinoic Acid Transfer And Protein-Protein Interaction Between The Cellular Retinoic Acid Binding Protein And The Retinoic Acid Receptor Probed By Hydrogen Deuterium Exchange Mass Spectrometry
Pure sciences Cellular retinoic acid binding proteins Hydrogen deuterium exchange Protein-protein interactions Retinoic acid receptors Retinoic acid
2014/12/11
Retinoic acid (RA) is the most potent metabolite of vitamin A and is utilized in signaling pathways that control many cellular events. Cellular retinoic acid binding proteins I and II are carriers of ...
The role of the ER glucosyltransferase in the quality control of glycoprotein maturation
Pure sciences Biological sciences Endoplasmic reticulum Glycoprotein Glycoprotein glucosyltransferase 1 Protein folding Protein maturation Glucosyltransferase
2014/12/11
N-linked glycans serve as quality control tags in the eukaryotic secretory pathway. The endoplasmic reticulum (ER) protein UDP-glucose: glycoprotein glucosyltransferase 1 (GT1) is the main enzyme that...
The Parkin-like ubiquitin E3 ligase Ariadne-1 in the mammalian brain: Potential implications for neurodegenerative disease
Parkinson's disease movement disorders dopaminergic neurons gene encoding protein ubiquitin proteasome system enzyme E3 ubiquitin ligase
2014/12/10
Parkinson’s disease (PD) is a movement disorder characterized by a massive loss of dopaminergic neurons of nigrostriatal origins. Several genes associated with familial cases of PD encode proteins tha...