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Alternative messenger RNA (mRNA) splicing is a fundamental process of gene regulation, and errors in RNA splicing are known to be associated with a variety of different diseases. However, there is cur...
In current research related to improving cancer treatments, one promising area of research is the effort to find ways to selectively pinpoint and target cancer cells while minimizing effects on health...
COLUMBUS, Ohio – New research suggests that a protein only recently linked to cancer has a significant effect on the risk that breast cancer will spread, and that lowering the protein’s level in cell ...
Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability...
University of Queensland researchers have discovered a protein in cells that could block the escape route of potentially cancerous cells and stop them spreading to other parts of the body.
Wavelet transform of polarized fluorescence spectra of human breast tissues is found to localize spectral features that can reliably differentiate normal and malignant tissue types. The intensity diff...
Mining gene expression profiles has proven valuable for identifying metagenes, defined as linear combinations of individual genes, serving as surrogates of biological phenotypes. Typically, such metag...
Signal Transducer and Activator of Transcription 4 (STAT4) is an important transcription factor activated by IL-12 signaling. Activated STAT4 is essential for Th1 cell differentiation, a process chara...
Abstract: The fluctuations in the elastic light scattering spectra of normal and dysplastic human cervical tissues analyzed through wavelet transform based techniques reveal clear signatures of self-s...
The nearby Lynx-Cancer void is a good laboratory to study the effect of very rarefied environment on the evolution of the least massive dwarf galaxies. A recently compiled sample of this void’s galaxi...
Does the void environment have a sizable effect on the evolution of dwarf galaxies? If yes, the best probes should be the most fragile least massive dwarfs.We compiled a sample of about one hundred dw...
Short single-walled carbon nanotubes (SWNTs) functionalized by PEGylated phospholipids are biologically non-toxic and long-circulating nanomaterials with intrinsic near infrared photoluminescence (NI...
Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To dev...
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring...
We propose a rapid and label-free quantitative evaluation of anti-cancer drug efficacy in apoptosis using live cancer cells cultured on a sensor chip. The resultant custom-made, high-precision surface...

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