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Mining gene expression profiles has proven valuable for identifying metagenes, defined as linear combinations of individual genes, serving as surrogates of biological phenotypes. Typically, such metag...
Signal Transducer and Activator of Transcription 4 (STAT4) is an important transcription factor activated by IL-12 signaling. Activated STAT4 is essential for Th1 cell differentiation, a process chara...
Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To dev...
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring...
Researchers at The University of Queensland have helped identify genes that could hold the key to treating a common and deadly type of breast cancer. The discovery suggests a vaccine could be develope...
A gene-based test is now available to identify smokers and ex-smokers at greatest risk of getting lung cancer. The test is the first in the world to provide a personalised estimate of lung cancer ris...
摘要为探讨肿瘤抑制基因APC结构及表达异常与胃癌发生、发展的关系,采用ARMS PCR检测胃癌中APC基因I1307K突变存在与否,免疫组织化学方法分析胃癌中APC蛋白表达水平。结果表明,在 62例胃癌高发区易感人群血液标本及45例胃癌中未检测到I1307K突变;胃癌(早期、进展期)中APC蛋白表达阳性率显著低于正常黏膜,进展期胃癌中APC蛋白表达阳性率显著低于早期胃癌,淋巴结转移阳性的胃癌中AP...
专著信息 书名 Improved efficacy of DNA vaccination against breast cancer by boosting with the repeat beta-hCG C-terminal peptide carried by mycobacterial heat-shock protein HSP65. 语种 英文 撰写或编译 作者 Yi H,Rong Y...
专著信息 书名 E-cadherin gene C-160A promoter polymorphism and risk ofnon-cardia gastric cancer in a Chinese population 语种 英文 撰写或编译 作者 Yan Lu,Yao-Chu Xu,Jing Shen,Rong-Bin Yu,Ju-Yin Niu,Jian-Tao Guo,Xu Hu,H...
专著信息 书名 Interleukin-1B gene promoter variants are associated withan increased risk of gastric cancer in a Chinese population 语种 英文 撰写或编译 作者 Jie Yang,Zhibin Hu,Yaochu Xu,Jing Shen,Juyin Niua,Xu Hu,Jian...
期刊信息 篇名 nm23-H1 transfection can regulate the expression of downstream genes related to “Lung Cancer metastasis Suppress casecade” and reverse the metastatic phenotype of human high metastasis large c...
期刊信息 篇名 Exon 3 polymorphisms and haplotypes of O(6)-methylguanine-DNA methyltransferase and risk of bladder cancer in southern China: A case-control analysis 语种 英文 撰写或编译 撰写 作者 Li C,Liu J,Li A,Qian L,W...
期刊信息 篇名 Expression and function of classical protein kinase C isoenzymes in gastric cancer cell line and its drug-resistant sublines.. 语种 英文 撰写或编译 作者 韩英,韩者艺 第一作者单位 刊物名称 World J Gastroenterol 页面 2002 ;...
期刊信息 篇名 Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis 语种 英文 撰写或编译 撰写 作者 Zhang Z(通讯作者),Xu Y...

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