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Engineers design sutures that can deliver drugs or sense inflammation（图）
输送药物 感知炎症 缝合线 生物衍生
2023/6/5
Inspired by sutures developed thousands of years ago, MIT engineers have designed “smart” sutures that can not only hold tissue in place, but also detect inflammation and release drugs.
One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can accou...
When Sharif Tabebordbar was a teenager, his father began having trouble walking. Soon, he became wheelchair-bound and was diagnosed with a rare genetic muscle disease.
Drug delivery capsule could replace injections for protein drugs（图）
药物输送胶囊 蛋白质药物 注射剂 单克隆抗体
2023/6/19
In recent years, scientists have developed monoclonal antibodies — proteins that mimic the body’s own immune defenses — that can combat a variety of diseases, including some cancers and autoimmune dis...
Plant-derived chemicals called cardenolides have long been used to treat heart disease and have shown potential as cancer therapies. But the compounds are toxic, making it difficult for doctors to pre...
New method for tapping vast plant pharmacopeia to make more effective drugs
New method plant pharmacopeia more effective drugs
2017/4/27
These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves f...
Innovative Sensor Can Screen Toxic Drugs,Help Develop Biomaterials,and Much More
Innovative Sensor Screen Toxic Drugs Help Develop Biomaterials Much More
2017/4/27
Researchers at the University of California, Riverside have found an innovative new use for a simple piece of glass tubing: weighing things. Their glass tube sensor will help speed up chemical toxicit...
Laser activated gold pyramids could deliver drugs,DNA into cells without harm
Laser activated gold pyramids deliver drugs DNA cells without harm
2017/3/30
The ability to deliver cargo like drugs or DNA into cells is essential for biological research and disease therapy but cell membranes are very good at defending their territory. Researchers have devel...
Scientists model outer membrane of 12 bacterial species to speed new drugs for 'bad bugs'
Scientists model membrane 12 bacterial species speed new drugs bad bugs
2016/11/4
As bacteria change their behavior to foil the drugs designed to kill them, illnesses that were once relatively easy to treat become difficult to cure. The phenomenon is known as antibiotic resistance,...
Marine Biodiversity and the Medicine Cabinet:The Status of New Drugs from Marine Organisms
Marine Biodiversity Medicine Cabinet New Drugs Marine Organisms
2015/8/13
Biodiversity provides the foundation in Nature for the production of diverse chemical compounds now used to treat human disease. Biodiversity translates to genetic uniqueness, which in turn results in...
The Oceans and Human Health:The Discovery and Development of Marine-Derived Drugs
Oceans and Human Health Discovery and Development Marine-Derived Drugs
2015/8/4
I am honored to have been invited to present the Second Annual Roger Revelle Commemorative Lecture. Although I never had the opportunity to meet or work with Dr. Revelle, his depth and breadth of know...
Sex,Drugs,and Sea Slime:The Oceans' Oddest Creatures and Why They Matter
Sex；Drugs；Sea Slime Oceans' Oddest Creatures Why They Matter
2015/7/13
Ellen Prager's book presents an entertaining account of the lives of many marine organisms. Its stories are understandable, fun to read, and focus on describing the curious attributes and mysterious l...
Development of Mass Spectrometry-Based Methods for Quantitation and Characterization of Protein Drugs: Transferrin as a Model Drug Delivery Vehicle
Mass Spectrometry O18 labeling Protein quantitation Transferrin
2014/11/20
In the last two decades, protein drugs have enjoyed a rapid growth and achieved a tremendous success in treating human diseases. However, the presence of physiological barriers greatly impedes the eff...
While many students took a well-earned break over summer, Brisbane woman Cindy Bermudez spent her holidays studying plants, bacteria and fungi in an effort to find treatments for infectious diseases.
Seed genes could provide basis for affordable therapeutic drugs
therapeutic drugs Seed genes
2014/7/15
Queensland scientists are unlocking the benefits of a protein found in seeds of a spiky red fruit that could lead to the development of more affordable medicines made from plants.