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中国科学院瘤内基因编辑增效ACT疗法研究获进展（图）
瘤内基因 编辑增效 ACT疗法
2023/5/18
过继T细胞转移（adoptive T-cell transfer，ACT）疗法是颇具前景的肿瘤免疫疗法，但对实体瘤效果欠佳，亟需通过学科交叉来发展针对实体瘤增效的新理念和新技术。近日，中国科学院过程工程研究所生化工程国家重点实验室研究员魏炜团队与浙江大学药学院教授平渊团队交叉合作，通过非侵入手段激活实体瘤的基因编辑，同时调控实体瘤物理和免疫微环境，显著提升了多种ACT疗法对实体瘤的疗效。相关研究成...
中国科学院过程工程研究所在瘤内基因编辑增效ACT疗法研究方面取得新进展（图）
瘤内 基因编辑 增效ACT疗法
2023/5/19
过继T细胞转移（adoptive T-cell transfer，ACT）疗法是极具前景的肿瘤免疫疗法，但对实体瘤效果欠佳，亟需通过学科交叉来发展针对实体瘤增效的新理念和新技术。近日，过程工程所生化工程国家重点实验室与浙江大学药学院交叉合作，通过非侵入手段激活实体瘤的基因编辑，并同时调控实体瘤物理和免疫微环境，显著提升了多种ACT疗法对实体瘤的疗效。相关工作发表于Nature Nanotechno...
Genomic data 'catch corals in the act' of speciation and adaptation（图）
Genomic data catch corals act speciation adaptation
2020/11/13
A U.S. National Science Foundation-funded study led by University of Hawai‘i at Mānoa researchers has revealed that diversity in Hawaiian corals is likely driven by co-evolution among t...
Plants Under Heat Stress Must Act Surprisingly Quickly to Survive（图）
Plants Under Heat Stress Quickly to Survive
2017/9/5
In new results reported in The Plant Cell, molecular biologist Elizabeth Vierling at the University of Massachusetts Amherst and colleagues in India and China report finding a crucial mechanism that p...
Young Stellar System Caught in Act of Forming Close Multiples
Young Stellar System Caught Forming Close Multiples
2016/11/4
For the first time, astronomers have seen a dusty disk of material around a young star fragmenting into a multiple-star system. Scientists had suspected such a process, caused by gravitational instabi...
The concept that biodiversity feeds upon itself is an old idea, but it’s difficult to prove because it requires biologists to simultaneously catch several species red-handed just as they are becoming ...
Death associated lepidopteran DALP, and its mammalian ortholog Hic-5, act as negative regulators of muscle differentiation
Vertebrates muscle differentiation muscle cells trunk limbs satellite cells cell apoptosis molecular regulation gene
2014/12/11
During muscle differentiation in vertebrates, myoblasts initially form in somites and then migrate to proper locations in the trunk and limbs. Once there, these cells are faced with one of three choic...
HOUSTON — (Nov. 2, 2014) — A disappearing act was the last thing Rice University physicist Randy Hulet expected to see in his ultracold atomic experiments, but that is what he and his students produce...
Supernova caught in the act by Palomar Transient Factory
Supernova caught in the act Palomar Transient Factory
2014/6/12
Supernovae—stellar explosions—are incredibly energetic, dynamic events. It is easy to imagine that they are uncommon, but the universe is a big place and supernovae are actually fairly routine. The pr...
The 2010 Korean soil preservation act: Will stabilization techniques still be feasible?
Korean MoE solidification/stabilization (S/S) total extraction aqua regia residual phase
2017/4/11
Korean Ministry of Environment (MoE) has implicated regulations to determine if the levels of environmental contaminants
exceed regulations levels. The Korean MoE adopted a partial extraction method ...
Features in the primordial spectrum: new constraints from WMAP7+ACT data and prospects for Planck
Features primordial spectrum constraints WMAP7+ACT data prospects Planck
2011/10/19
We update the constraints on possible features in the primordial inflationary density perturbation spectrum by using the latest data from the WMAP7 and ACT Cosmic Microwave Background experiments. The...
The Advanced Encryption Standard (AES) is widely recognized as the most important block cipher in common use nowadays. This high assurance in AES is given by its resistance to ten years of extensive ...
Classification of non-symplectic automorphisms on $K3$ surfaces which act trivially on the Néron-Severi lattice
K3 surface non-symplectic automorphism
2010/12/10
We treat non-symplectic automorphisms on K3 surfaces which act trivially on the N´eron-Severi lattice. In this paper,we classify non-symplectic automorphisms of prime-power order,especially 2-po...
RIPPLE MARKS—THE STORY BEHIND THE STORY | Canyon "Ghost" Critical to Stream Ecosystems: Cougars Act as Guardians of Fish, Frogs • "Wavelet" Math Translates Whale Song into Art • Fire in the Sky, Smoke in the Water: Queen of American Lakes Under Siege from Fireworks Displays? • Jellyfish "Blooms" Signal Ailing Seas Ahead: Jellywatchers Help Scientists Track Locations
Ghost cat cat puma tupi predators habitat
2015/7/7
The ghost cat, it's been called, this feline that roams backcountry from the Yukon to Chile. It has dozens of names, from panther, to puma, to mountain lion. But its best descriptor, perhaps, is couga...
Ecological balancing act（图）
Phytoplankton diversity Ecological balancing act the ocean’s physical dynamics
2010/3/24
Phytoplankton are single-celled organisms that serve as the base of the marine food web and provide half the oxygen we breathe on Earth. They also play a key role in global climate change by removing ...