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提供了由哺乳动物YAP蛋白或具有转录控制活性的片段的融合蛋白的与细胞全能性和转录激活结构域相关的基因编码的蛋白、编码核苷酸序列、表达载体及其组合物,以及使用该融合蛋白诱导多能干细胞的方法。
本发明提供了一种下调或不表达单胺氧化酶的重组广谱绿僵菌, 或其中色胺含量高于野生型广谱绿僵菌,重组广谱绿僵菌是菌株本身,菌株后代,菌株产生的分生孢子,菌株产生的菌丝体或它们的任意组合。 从重组广谱绿僵菌中敲除单胺氧化酶基因,显著提高了绿僵菌中色胺的浓度, 从而显著提高其杀虫效率,使野生型广谱绿僵菌的半致死时间LT50从7.33±0.445天缩短到6.136±0.488天。 本发明的重组广谱绿僵菌对...
中国科学院动物研究所专利:Recombinant Metarhizium acridum, preparation method therefor and use thereof。
Improving the sensitivity of protein-protein interaction detection and protein structure probing is a principal challenge in cross-linking mass spectrometry (XL-MS) data analysis. In this talk, we pro...
A new imaging technique opens a path toward long-term study of blood vessels in aging brains and could help predict neurodegenerative diseases decades before symptoms begin.
One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can accou...
Our brains are charged with the task of directing most of the processes needed for our bodies to function. As such, they consume roughly 20% of our body’s metabolic energy, even while we’re resting.
In recent years, scientists who study gene expression in cells have used a method that essentially pins a tail on RNA and tracks their whereabouts. However, certain types of RNA evade the process. Now...
Biological engineers have devised a way to program memories into bacterial cells by rewriting their DNA. The new DNA writing technique, which the researchers call HiSCRIBE, is much more efficient than...
A new study by chemists at the University of Arkansas shows that X-ray crystallography, the standard method for determining the structure of proteins, may provide inaccurate information about a critic...
The aim of this study was to evaluate the effect of different thawing protocols (slow (P1), medium (P2), and fast (P3)) on percentage of motile sperm (MOT) and percentage of sperm cells with intact me...
These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves f...
The wind rushing between skyscrapers is a substantial hurdle for anyone interested in operating small drones in urban areas. Yet, pigeons seem to have little trouble maneuvering through turbulent city...
A new computational method can improve the accuracy of gene expression analyses, which are increasingly used to diagnose and monitor cancers and are a major tool for basic biological research.Research...
Temperature has a significant influence on development rates of insects and mites. Many parametric models were built to describe the temperature-dependent development rates. However, these models pro...

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