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Sparse, small, but diverse neural connections help make perception reliable, efficient（图）
神经连接 丘脑输入 视觉皮层神经元 脑科学
2023/6/5
The brain’s cerebral cortex produces perception based on the sensory information it’s fed through a region called the thalamus.
A penalized matrix decomposition, with applications to sparse principal components and canonical correlation analysis
Canonical correlation analysis DNA copy number Integrative genomic analysis L1 Matrix decomposition Principal component analysis Sparse principal component analysis SVD.
2015/8/21
We present a penalized matrix decomposition (PMD), a new framework for computing a rank-K approximation for a matrix. We approximate the matrix X as X ˆ = k K=1 dkukvk T , where dk, uk, and vk m...
A sparse regulatory network of copy-number driven expression reveals putative breast cancer oncogenes
twork copy-number driven expression reveals putative breast cancer oncogenes
2010/11/15
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring...