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Biosynthetic introduction of aryl bromide functionality into proteins
Aryl bromide proteins bacteria e. coli phenylalanine synthetase gene plasmid bear dihydrofolate reductase
2014/12/11
Incorporation of aryl bromide functionality into proteins was achieved via engineering the bacterial biosynthetic apparatus. A phenylalanine auxotrophic E. coli host was equipped with a phenylalanyl-t...
Overlapping and distinct functions for Gli proteins: Key mediators of hedgehog signaling in cell specification during embryonic development
Signals embryonic tissue cell differentiation the central nervous system the pituitary gland the pancreas cells
2014/12/11
Hedgehog (Hh) signaling is important for patterning and cell differentiation within many embryonic tissues. Hh is expressed in the notochord and the floor plate and acts as a morphogen in patterning o...
THE IDENTIFICATION AND CHARACTERIZATION OF A GROUP OF ER TPR-CONTAINING ADAPTER PROTEINS
cell biology endoplasmic reticulum tetratricopeptide repeats endoplasmic reticulum compartmentalization calcium homeostasis adapter proteins
2014/12/10
The endoplasmic reticulum (ER) is an organelle responsible for a variety of functions in all eukaryotic cells. Some of these functions are localized to specific regions in the ER, such as the ribosome...
Now researchers can see how unfolded proteins move in the cell（图）
unfolded proteins move in the cell
2014/12/30
CHAMPAIGN, Ill. — When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope -- a sort of cellular traffic camera -- University ...