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One reason it's so difficult to produce effective vaccines against some viruses, including influenza and HIV, is that these viruses mutate very rapidly. Mutation allows them to evade the antibodies ge...
Using the mouse egg as a model system for the study of intracellular calcium signaling mechanisms
Oscillation eggs fertilization cell model system inositol
2014/12/11
Mouse metaphase II (MII)-stage eggs exhibit oscillatory Ca2+ responses ([Ca2+]i oscillations) following fertilization. The wealth of information regarding Ca2+ signaling pathways in eggs has allowed t...
Target Recognition and Competitive Synaptogenesis in the Drosophila Giant Fiber System
competition Drosophila giant fiber guidance synaptogenesis
2014/12/10
The development of complex neural networks relies on a careful balance of environmental cues to guide and shape both ends of the eventual connection. However, the correct wiring of circuits whose comp...
“Recent research has found that cancer is already adept at using cyberwarfare against the immune system, and we studied the interplay between cancer and the immune system to see how we might turn the ...
UC Research Tests Which Nano System Works Best in Killing Cancer Cells（图）
UC Research Tests Nano System Works Best Cancer Cells
2014/3/20
In current research related to improving cancer treatments, one promising area of research is the effort to find ways to selectively pinpoint and target cancer cells while minimizing effects on health...
Immune system drives pregnancy complications after fetal surgery in mice（图）
Immune system drives pregnancy complications
2014/3/18
As a fetal surgeon at UC San Francisco, Tippi MacKenzie, MD, has long known that conducting surgery on a fetus to correct a problems such as spina bifida often results in preterm labor and premature b...
The Direct Reprogramming of Somatic Cells: Establishment of a Novel System for Photoreceptor Derivation
development genetic photoreceptor regeneration reprogramming retina
2015/5/22
Photoreceptors are a class of sensory neuronal cells that are deleteriously affected in many disorders and injuries of the visual system. Significant injury or loss of these cells often results in a p...
15 November 2006，Research led by King's scientists, and published online in the journal Nature, sheds new light on the development of the immune cells which are critical in fighting infection and some...
Systems Biology-Toward System-level Understanding of Biological Systems
Systems Biology-Toward System-level
2014/3/31
System Design: the strategies to modify and construct biological systems having desired properties can be devised based on definite design principles and simulations, instead of blind trial-and-error.
The technique was first developed for investigating small vessels with internal diameters down to around 100 μm by Mulcany & Halpern , in 1976,1977Multi Myograph System – 610M is suited to vessels wit...