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The influence of genetic susceptibility and calcium plus vitamin D supplementation on fracture risk
fracture bone mineral density genetic risk score calcium vitamin D postmenopausal women
2018/11/13
Background: Fracture is a complex trait, affected by both genetic and environmental factors. A meta-analysis of genome-wide association studies (GWASs) identified multiple bone mineral density (BMD) a...
Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals
nondigestible carbohydrates colorectal cancer calprotectin Wnt signaling epigenetics
2018/11/12
Background: Hyperactive Wnt signaling is frequently observed in colorectal cancer. Higher intakes of dietary fiber [nondigestible carbohydrates (NDCs)] and the fermentation product butyrate are protec...