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Genome-wide polymorphisms show unexpected targets of natural selection
population genomics natural selection
2015/12/11
Natural selection can act on all the expressed genes of an individual, leaving signatures of genetic differeniation or diversity at many loci across the genome. New power to assay these genome-wide ef...
Nonspecific Protein-DNA Binding Is Widespread in the Yeast Genome
Nonspecific protein-DNA binding Free energy of nonspecific protein-DNA binding Biomolecules
2012/5/2
Recent genome-wide measurements of binding preferences of ~200 transcription regulators in the vicinity of transcription start sites in yeast, have provided a unique insight into the cis- regulatory c...