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Nanorobotic system presents new options for targeting fungal infections（图）
Dental Medicine Bioengineering Robotics Research
2023/6/27
Infections caused by fungi, such as Candida albicans, pose a significant global health risk due to their resistance to existing treatments, so much so that the World Health Organization has highlighte...
AI system can generate novel proteins that meet structural design targets（图）
AI系统 新型蛋白质 可调蛋白质
2023/6/6
MIT researchers are using artificial intelligence to design new proteins that go beyond those found in nature.
Ateam of researchers led by Harvard and Broad Institute scientists has developed a new drug-delivery system using engineered DNA-free virus-like particles (eVLPs) that is able to edit genes associated...
Ateam of researchers led by Harvard and Broad Institute scientists has developed twin prime editing, a new, CRISPR-based gene-editing strategy that enables manipulation of gene-sized chunks of DNA in ...
When Sharif Tabebordbar was a teenager, his father began having trouble walking. Soon, he became wheelchair-bound and was diagnosed with a rare genetic muscle disease.
Off-Switch for CRISPR-Cas9 Gene Editing System Discovered
Off-Switch CRISPR-Cas9 Gene Editing System
2017/1/9
UC San Francisco researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial vi...
Fermentation Festival Leads to Rapid Response System at Center for Microbiome Innovation
Fermentation Festiva Response System at Center Microbiome Innovation
2016/5/6
The personalized collections of microorganisms and molecules found in, on and around us — known as our microbiome and metabolome, respectively — are increasingly recognized for their influences on eve...
CRISPR-Cas adaptive immune systems in prokaryotes boast a diversity of protein families and mechanisms of action, where most systems rely on protospacer-adjacent motifs (PAMs) for DNA target recogniti...
FACILITATING PHARMACOGENETIC ASSOCIATION STUDIES USING AN EXTENSIBLE GENOTYPE INFORMATION MANAGEMENT SYSTEM
Large-scale genome Clinical Pharmacology
2015/5/27
Large-scale genome data projects employing automated, high-throughput techniques have led to a deluge of genomic data that necessitate robust informatic solutions. COBRA-DB is an integrated web-based ...
System biology modeling : the insights for computational drug discovery
Drug Repositioning Machine Learning Side Effect
2015/5/26
Traditional treatment strategy development for diseases involves the identification of target proteins related to disease states, and the interference of these proteins with drug molecules. Computatio...
INTEGRATIVE SYSTEM BIOLOGY STUDIES ON HIGH THROUGHPUT GENOMICS AND PROTEOMICS DATASET
System Biology Genomics Proteomics
2015/5/26
The post genomic era has propelled us to the view that the biological systems are complex network of interacting genes, proteins and small molecules that give rise to biological form and function. The...
Implementation of a Laboratory Information Management System To Manage Genomic Samples
Laboratory Workflow Implementation Configuration
2015/5/26
A Laboratory Information Management Systems (LIMS) is designed to manage laboratory processes and data. It has the ability to extend the core functionality of the LIMS through configuration tools and ...
New technique uses bacteria's own CRISPR-Cas system to turn off genes
bacteria genes CRISPR-Cas system
2014/10/30
Researchers from North Carolina State University have developed a technique that co-opts an immune system already present in bacteria and archaea to turn off specific genes or sets of genes – creating...
线粒体DNA修复系统相关酶的研究进展 Progress of Enzyme in Mitochondrial DNA Repair System
线粒体DNA DNA修复 酶 研究进展
2008/1/10
摘要线粒体DNA（mtDNA）编码线粒体电子传递系统的亚单位以及构建翻译机器所需的各种rRAN和tRNA。mtDNA编码的每一个亚单位都是线粒体完成正常的氧化磷酸化过程所必需的，因此，线粒体DNA的完整性对于生物体的生存十分重要。长期以来，人们一直认为线粒体中不存在DNA的修复。近年来在线粒体提取物中却检测到了一定数量的修复因子，提示线粒体中存在DNA的修复。主要对线粒体修复系统中相关酶的研究进展...
期刊信息
篇名
Multivariate Calibration for a SupramolecularAnalytical System of Metals Porphyrin by an Ant Colony Algorithm
语种
英文
撰写或编译
作者
Ding Y-P,（1）
第一作者单位
刊物名称
Analytical Sciences
页面
2005, 21 (3): 218
出...