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汕头大学医学院药理学课件 Calcium Channel Blockers (CCB)。
汕头大学医学院药理学精品课程 Calcium Channel Blockers （CCB）
汕头大学 医学院 药理学 精品课程 Calcium Channel Blockers （CCB）
2013/11/7
汕头大学医学院药理学精品课程 Calcium Channel Blockers （CCB）。
Synthesis and Calcium channel antagonist activity of Nifedipine analogues with Chloroindolyl substituent
Synthesis Calcium channel antagonist activity Nifedipine analogues Chloroindolyl substituent
2010/1/6
Various diester analogues of nifedipine in which the ortho nitrophenyl group at position 4 were replaced by 3-chloro-1H-2-indolyl substituent, were synthesized and evaluated as calcium antagonists on ...
Synthesis and smooth muscle Calcium channel antagonist effect of Alkyl, Aminoalkyl 1,4-Dihydro-2,6-Dimethyl-4-Nitroimidazole-3,5 Pyridine Dicarboxylates
Ca+² channel antagonist DHP Arylpiperazine
2009/12/29
The discovery that 1,4-dihydropyridine (DHP) class of calcium channel antagonist inhibits the Ca+² influx represented a major therapeutic advance in the treatment of cardiovascular diseases such ...
Synthesis and smooth muscle Calcium channel antagonist effects of new derivatives of 1,4-Dihydropyridine containing Nitroimidazol substituent
Dihydropyridine Calcium channels antagonist GPILSM
2009/12/29
A group of racemic 3-[(2-hydroxyethyl), (2-Methoxyethyl), (2-acetylethyl) or (2-cyanoethyl)], 5- methyl, ethyl or isopropyl-1, 4-dihydro-2, 6-dimethyl-4-(1-methyl-5-nitro-2-imidazolyl)-3, 5-pyridinedi...
Heterogeneous expression of the voltage-gated calcium channel α2 subunit and the voltage-gated sodium channel α subunit in chicken spinal motoneurons
chicken spinal motoneurons voltage-gated sodium channel α subunit
2009/12/16
The localization of the voltage-gated calcium channel (VGCC) α2 and the voltage-gated sodium channel (VGSC) α subunits was immunohistochemically investigated in chicken spinal motoneurons. Approximate...
Synthesis and in vitro dual calcium channel antagonist-agonist activity of some 1, 4-Dihydo-2,6-dimethyl-3-nitro and cyano-4-(1-methyl-5-nitro-1H-imidazol-2-yl)-5-pyridinecarboxylates
Calcium channel antagonist-agonist activity Dihydropyridines QSAR
2009/12/14
Background and purpose of the study: The vasorelaxant action of the dihydropyridines (DHPs) provides many useful clinical indications. However, their negative effects on cardiac contractility is still...
Kinetic Spectrofluorometric Determination of Certain Calcium Channel Blockers via Oxidation with Cerium (IV) in Pharmaceutical Preparations
verapamil hydrochloride diltiazem hydrochloride nicardipine hydrochloride Cerium (IV)
2009/10/30
A simple and sensitive kinetic spectrofluorometric method was developed for the determination of some calcium channel blockers namely, verapamil hydrochloride, diltiazem hydrochloride, nicardipine hyd...
Comparison of effects of PKA catalytic subunit on Ih and calcium channel currents in rat dorsal root ganglion cells
PKA catalytic calcium channel currents rat dorsal root ganglion cells
2009/3/2
We investigated whether PKA-induced phosphorylation was involved in regulation of hyperpolarization-activated current (Ih) in rat dorsal root ganglion (DRG) cells. We examined the effect of the cata...
The Effect of Calcium Channel Blockers on Male Reproductive Potential
Calcium Channel Blockers Male Reproductive Potential
2008/12/23
The potential impact of calcium channel blockers on male fertility has been a topic of discussion for some time. In this edition of Androlog, Dr Grace Centola describes her efforts in the management o...
Lack of Voltage-Dependent Calcium Channel Opening During the Calcium Influx Induced by Progesterone in Human Sperm. Effect of Calcium Channel Deactivation and Inactivation
Intracellular calcium mammalian sperm membrane potential membrane potential-sensitive dyes
2008/12/22
Progesterone induces calcium influx and acrosomal exocytosis in human sperm. Pharmacologic evidence suggests that voltage-dependent calcium channels (VDCCs) are involved. In this study, membrane p...