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Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice
aged mouse immunosuppression phospholipase A2 restraint stress specific antibody
2010/11/16
Background: We have recently found that exposure to acute restraint stress suppresses antigen-specific antibody production, including IgE, in a murine model of allergic rhinitis. Although age-related ...
应用胎儿特异性抗体HbF（γ链）标记法无创性产前基因诊断DMDUse of Fetal Specific Antibody—HbF to Detect Fetal Erythroblasts for Non-invasive Prenatal Diagnosis of DMD
有核红细胞 免疫组化 Duchenne型肌营养不良症 (DMD)
2008/1/6
摘要以孕8~26周孕妇外周血为材料，经过Percoll密度梯度离心初步富集，胎儿细胞特异性抗体—HbF标记、识别胎儿有核红细胞，母体和胎儿有核红细胞的精确区分是以胎儿和成人血红蛋白的组成差异为基础的。胎儿细胞胞浆黄染，而具有成人血红蛋白的母体细胞没有颜色。显微操作法获取全部阳性细胞后，以其全基因组扩增（PEP）的产物为模板，进行性别检测、DMD基因的多重PCR检测和STR连锁分析。结果，20名孕妇...