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2017老化和老化相关疾病的机制 Keystone Symposia（2017 Keystone Symposia on Aging and Mechanisms of Aging-Related Disease）
Aging-Related Disease protein homeostasis
2017/3/7
Populations are aging rapidly worldwide, particularly in Asia, driving a strong interest in aging/longevity research. This Keystone Symposia meeting will capture the cutting-edge front of this excitin...
Mechanisms of translational regulation in the pancreatic β cell stress response
Diabetes Islet ER stress Pdx1
2015/5/22
The islet beta cell is unique in its ability to synthesize and secrete insulin for use in the body. A number of factors including proinflammatory cytokines, free fatty acids, and islet amyloid are kno...
Morphological Assessment of Basic Multicellular Unit Resorption Parameters in Dogs Shows Additional Mechanisms of Bisphosphonate Effects on Bone
basic multicellular unit alendronate
2014/12/4
Bisphosphonates (BPs) slow bone loss by reducing initiation of new basic multicellular units (BMUs). Whether or not BPs simply prevent osteoclasts from initiating new BMUs that resorb bone or also red...
Immune Mechanisms in Drug Allergy
autologous cytotoxicity drug hypersensitivity epidermal HLA immunologic T-lymphocytes toxic
2010/11/18
In the last decade several teams of researchers obtained in vitro drug-specific human T-cell clones, in a variety of clinical types of drug eruptions. These clones were produced from blood or skin mon...
Mechanisms of eosinophilic inflammation in the mucosa of the nasal cavity and paranasal sinus
allergic rhinitis eosinophil eotaxin
2010/11/25
More than one mechanism contributes to persistent increases in eosinophils in the nasal cavity and paranasal sinus. The levels of eotaxin in lavage samples obtained after antigen challenge showed stro...