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The effects of 3-benzoyl-1-methyl-4-phenyl-4 piperidinolhydrochloride (C1), indomethacin, nimesulide and rofecoxib on cyclooxygenase activities in carrageenan-induced paw edema model
3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride COX enzymes inflammation
2010/10/14
The aim of this study was to investigate the effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride (C1), which is a structural and also non-classical isomer of bis Mannich base, bis (3-ar...
Combination of inulin and time dependent polymethacrylates as a coating system to achieve colonic delivery of indomethacin
Colonic drug delivery Indomethacin Inulin Eudragit RS Eudragit RL
2009/11/26
Background:In the previous study it was shown that films prepared from inulin (In) in combination with Eudragit RS (ERS) and RL (ERL) were susceptible to inulinase. Purpose: The aim of this work was t...