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真菌性角膜炎是一种由致病真菌引起的致盲率极高的眼部感染性疾病。若感染早期未及时诊断和治疗,炎症则会迅速进展,引起角膜混浊、溃疡、穿孔,不仅会导致严重的眼内炎,还会导致颅内感染扩散。那他霉素是唯一一个被美国食品药品监督管理局批准用于控制真菌性角膜炎的滴眼液,具有抗菌谱广、抗菌能力强、不良反应少等优点。但是那他霉素难溶于水,目前市面上只有5%的那他霉素悬浊液(那特真)存在。那特真价格昂贵,除此之外,由...
Applications for this meeting must be submitted by May 27, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be st...
The history of substance abuse in Malaysia can be divided into pre- and post-independent era. In pre-independence, the main drug of abuse was opium which was initially consumed by immigrants from Chin...
Germline mutations have been associated with generation of various types of tumour. In this study, we investigated genetic alteration of germline tumours that affect the drug sensitivity of cells. Alt...
Patients’ Willingness to Discuss Trade-offs to Lower Their Out-of-Pocket Drug Costs.
Cambridge, Mass. September 25th, 2014 — Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system ...
A molecular ‘target’ that could lead to a drug to fight leukaemia is in the sights of a team of University of Queensland researchers.
Background: There is a high risk of tuberculosis (TB) infection among injecting drug users (IDUs).
The University of Queensland researchers are seeking to identify more effective ways of treating drug addiction to tackle the perceived prevalence of injecting drug use worldwide.
An implant that can be wirelessly programmed to release drugs inside the body has been successfully tested in humans. Researchers say that the device could save patients from the painful ritual of dai...
Drug-induced liver injury (DILI) limits the development and application of many therapeutic compounds and presents major challenges to the pharmaceutical industry and clinical medicine. Acetaminophen-...
Antimicrobial resistance has become a major health problem worldwide, but marked variations in resistance profiles of bacterial pathogens are found among countries and in different patient settings, e...
A 63-year-old woman with typical chest pain referred to our center. Her risk factors were hypertension (HTN), hyperlipidemia (HLP), diabetic mellitus (DM), and smoking. Coronary angiography (CAG) reve...
Determination of sensitivity of isolated bacteria to consuming antibiotics could help clinician use appropriate antibiotics because due to unavailability of appropriate alternative antibiotics for hos...

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