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Mechanisms of Glybenclamide-Mediated Anti-Arrhythmia and Ischemic Conditionining in a Rat Model of Myocardial Infarction: Role of yohimbine Treatment
ATP sensitive potassium channels Hypoglycemic sulfonylurea compounds Myocardial ischemia Arrhythmia Yohimbin
2009/6/23
Glibenclamide (Glyburide), a widely used second-generation sulfonylurea hypoglycemic agent, is a known specific blocker of adenosine triphosphate (ATP) sensitive potassium (K+) channels. Although the ...
The role of K –ATP channel in the preconditioning effect of magnesium in the rat isolated heart
K-ATP channel infarction ischaemia Diazoxide Glibenclami
2010/4/12
There is growing interest for beneficial effect of Mg in the cardiovascular disorders. A number of cardiovascular disorders including myocardial infarction, arrhythmias and congestive heart failure ha...
Evaluation of cardiovascular effect of Pycnocycla spinosa Decne. exBoiss. var. spinosa extract in anaesthetized rat
Pycnocycla spinosa var. spinosa Hydroalcoholic extract Blood pressure Heart rate
2010/2/5
Hydroalcoholic extract of Pycnocycla spinosa Decne. exBoiss. var. spinosa has in vitro spasmolytic action, and at oral dose of 250g/kg inhibits castor oil induced diarrhoea in mice. In this in...