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Correlation of systemic lupus erythematosus disease activity with classical complement (CH50) function and related protein levels
Systemic lupus erythematosus CH50 C3 C4 C3d C4d SC5b-9 inactive flare
2009/12/9
Background: The components of the classical complement pathway play an important role in the pathogenesis of systemic lupus erythematosus (SLE) and are reportedly useful biomarkers of disease activity...
Urinary Eosinophil-derived Neurotoxin Concentrations in Patients with Atopic Dermatitis: A Useful Clinical Marker for Disease Activity
atopic dermatitis eosinophil eosinophil-derived neurotoxin visual analogue scale
2010/11/18
Background: It has been reported that measurements of eosinophil-derived neurotoxin (EDN) may be useful for identifying eosinophil activities in allergic diseases including atopic dermatitis.
Methods...
A Case of Angioedema Associated with Decreased C1 Inhibitor Activity
Angioedema C1 inhibitor complement HAE triggering factor
2010/11/18
Background: We report a case of a 31-year-old woman who began to notice swelling of her arms at age 20. She was once given a diagnosis of cellulitis, but her symptoms spontaneously resolved. The patie...
Eosinophil hypersegmentation is a possible marker to monitor the disease activity of atopic dermatitis
atopic dermatitis eosinophils nuclear lobes of eosinophils
2010/11/25
Background: In the present study, we tried to clarify whether nuclear hypersegmentation of peripheral blood eosinophils is correlated with peripheral eosinophil counts and/or the activity of atopic de...