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Interaction of different doses of Aspartame with Morphine-induced antinociception in the presence of MK-801,a NMDA antagonist
Antinociception Morphine Aspartame Sweetening agents NMDA
2010/1/4
This study was designed to investigate the relative role of sweetness and comparative effects of different taste sensation of the non - caloric sweetener , aspartame on pain and its interaction with M...
Synthesis and smooth muscle Calcium channel antagonist effects of new derivatives of 1,4-Dihydropyridine containing Nitroimidazol substituent
Dihydropyridine Calcium channels antagonist GPILSM
2009/12/29
A group of racemic 3-[(2-hydroxyethyl), (2-Methoxyethyl), (2-acetylethyl) or (2-cyanoethyl)], 5- methyl, ethyl or isopropyl-1, 4-dihydro-2, 6-dimethyl-4-(1-methyl-5-nitro-2-imidazolyl)-3, 5-pyridinedi...
The effect of acute Lithium and AMI-193,a new 5HT2 antagonist,on Apomorphine-induced pecking in pigeon
Pecking Serotonin receptors Apomorphine
2009/12/24
Intramascular (IM) administration of apomorphine (a mixed D1/D2 dopamine receptors agonist 0.2-1.6 mg/kg) induced pecking, a stereotype behavior in pigeons in a dose- dependent manner. In this study t...
Synthesis and in vitro dual calcium channel antagonist-agonist activity of some 1, 4-Dihydo-2,6-dimethyl-3-nitro and cyano-4-(1-methyl-5-nitro-1H-imidazol-2-yl)-5-pyridinecarboxylates
Calcium channel antagonist-agonist activity Dihydropyridines QSAR
2009/12/14
Background and purpose of the study: The vasorelaxant action of the dihydropyridines (DHPs) provides many useful clinical indications. However, their negative effects on cardiac contractility is still...