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Comparison of Bypassing Agents in Bleeding Reduction in Treatment of Bleeding Episodes in Patients With Haemophilia and Inhibitors
Haemophilia Meta-Analysis Bleeding
2015/10/16
Context: Mild-to-moderate bleeding disorders in haemophilia are primarily treated via recombinant activated factor VII a (rFVIIa) or activated prothrombin complex concentrate (aPCC). However, the effi...
Medicinal Chemistry and Therapeutic Relevance of Angiotensin-Converting Enzyme Inhibitors
medicinal chemistry angiotensin converting enzyme inhibitors (ACEIs) therapeutics critical thinking
2018/5/2
Chemical Basis of Drug Action (PHA337 and PHA447) is a required 2-semester course sequence taught to second-professional year pharmacy students at Creighton University in both the campus and distance-...
The Chemically Elegant Proton Pump Inhibitors
medicinal chemistry proton pump inhibitors gastroesophageal reflux disease ulcer
2018/4/19
Medicinal chemistry instruction at Creighton University is designed to provide an in-depth scientifically grounded and clinically relevant learning experience for pharmacy students. Each topic covered...
Mechanism-Based Inhibitors of Deoxythymidine Synthesis as Neoplastic Agents
Mechanism-Based Inhibitors Deoxythymidine Synthesis Neoplastic Agents
2016/3/10
5-Fluorouracil and methotrexate are antimetabolites widely used in the treatment of neoplastic disease. They act by inactivating the two enzymes involved in the biosynthesis of the pyrimidine nucleoti...