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In vitro effect of current antimalarial drugs on the survival of paired Schistosoma mansoni adult worms and their egg production
antischistosomal drugs antimalarial drugs Schistosoma mansoni
2010/12/10
Some field trials have already demonstrated the high antischistosomal potential of combination therapies using Artesunate (ART) and current antimalarial drugs (Boulanger et al., 2007; Mohamed et al., ...
Ischemia reperfusion dysfunction changes model-estimated kinetics of myofilament interaction due to inotropic drugs in isolated hearts
Ischemia reperfusion dysfunction model-estimated kinetics myofilament interaction inotropic drugs
2010/2/26
We found that IR injury resulted in reduced myofilament Ca2+ sensitivity, and decreased cross-bridge association and dissociation rates. Dopamine (8 μM) reduced myofilament Ca2+ sensitivity before, bu...