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Multi-scale analysis of morphology, mechanics, and composition of collagen in murine osteogenesis imperfecta
Atomic force microscopy Raman spectroscopy Reference point indentation MicroCT crystallinity modulus
2015/1/12
Osteogenesis imperfecta is a rare congenital disease commonly characterized by brittle bones caused by mutations in the genes encoding Type I collagen, the single most abundant protein produced by the...
Multi-scale Analysis of Bone Chemistry, Morphology and Mechanics in the oim Model of Osteogenesis Imperfecta
Atomic force microscopy Raman Spectroscopy Reference Point Indentation MicroCT Crystallinity Modulus
2014/11/6
Osteogenesis imperfecta is a congenital disease commonly characterized by brittle bones and caused by mutations in the genes encoding Type I collagen, the single most abundant protein produced by the ...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM Tension Nanoscale Ultrastructure Modulus
2014/11/6
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
In Vitro Analysis of Biodegradable Polymer Blend/Hydroxyapatite Composites for Bone Tissue Engineering
biodegradable hydroxyapatite poly(caprolactone) PLGA tissue engineering
2009/12/22
Blends of biodegradable polymers, poly(caprolactone)
and poly(D,L-lactic-co-glycolic acid), have been examined
as scaffolds for applications in bone tissue engineering.
Hydroxyapatite granules have...
CAE Stress Field Analysis by Shape Factor of Artificial Organs for Aortic Root Replacement
Aortic valve Valsalva sinus artificial valve CAD/CAE
2009/8/24
The sinuses of Valsalva are known to contribute to the normal function. Therefore, the Valsalva graft is being widely used in the aortic root replacement. On the other hand, the artificial valve is de...
Design Improvement of the Rotary Blood Pump by Computational Fluid Dynamics Analysis
artificial heart ventricular assist device axial flow blood pump computational fluid dynamics
2009/6/9
In this study, the pump performance derived from CFD analysis coincided well with the experimental results. From the results of the CFD analysis, the existence of reverse flows was found in the inflow...
Analysis of QT Prolongation Using Cardiac Action Potential Simulation
QT interval prolongation remodeling IKs current KCNE1 Luo-Rudy model
2009/6/9
In heart failure, QT interval and action potential duration (APD) is prolonged and IKs, a slow component of delayed rectifier potassium current, decreases. We have reported that the KCNE1 gene, coding...
Bone formation in β-tricalcium phosphate-filled bone defects of the rat femur：Morphometric analysis and expression of bone related protein mRNA
β-tricalcium phosphate-filled bone rat femur Morphometric analysis bone related protein mRNA
2009/3/2
The purpose of the current study was to evaluate the bone formation when β-tricalcium phosphate (TCP) was implanted in bone defects of rat femurs. β-TCP granules were applied to defects created in t...
Analysis of Regulatory Interaction Networks from Clusters of Co-expressed Genes
Regulatory Interaction Networks Co-expressed Genes
2009/12/24
Analysis of Regulatory Interaction Networks from Clusters of Co-expressed Genes.
ANALYSIS OF THE ESSENTIAL OILS OF TWO CULTIVATED BASIL (OCIMUM BASILICUM L.) FROM IRAN
Ocimum basilicum Lamiaceae Essential oil Methyl chavicol Citral
2010/2/1
The chemical compositions of the essential oils of Ocimum basilicum L. cv. purple and Ocimum basilicum L. cv. green cultivated in Iran were investigated by GC-MS. Twenty constituents (98.5% of the tot...
Walking with a rollator unloaded the ankle and especially the knee extensors, increased the hip flexion and thus the contribution of hip extensors to produce movement. Thus, rollator walking did not r...