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PfCP-2.9/PfCSP-2疟疾联合疫苗免疫效果血清学评价研究
疟疾疫苗 血清学 间接ELISA
2015/12/18
对PfCP-2.9/PfCSP-2疟疾联合疫苗所诱发的特异性IgG抗体进行分析评价。 方法 将5只新西兰白兔分为两组，其中免疫组3只，非免疫组2只。免疫组接种PfCP-2.9/PfCSP-2疟疾联合疫苗，非免疫组注射生理盐水。连续3次免疫后，采集血液样本并经间接ELISA检测其IgG抗体水平。根据非免疫组兔的吸光度数值（A值）计算临界值。临界值=2.1×非疫苗免疫组兔A值均值。若免疫组兔吸光度值高...
We show in an idealized model that the narrow sense (linear) heritability from d autosomal SNPs can be estimated without bias from n independently sampled individuals, by a method of moments strategy ...
In microarray studies, an important problem is to compare a predictor of disease outcome
derived from gene expression levels to standard clinical predictors. Comparing them on the same
dataset that ...
Complex Systems Analysis of Arrested Neural Cell Differentiation during Development and Analogous Cell Cycling Models in Carcinogenesis
Cell cycling control of cell division and the neoplastic transformation in carcinogenesis essential roles of high c-Myc p27 Inhibition p53 inactivation and hTERT activation of Telomerase biosynthesis in Malignant Cell Transformation Rational Clinical trials Individualized Medicine and potential for optimized Radio-Chemo- Gene- and Immuno- therapies of Cancers Ł ukasiewicz models of Genetic Networks Genome and cell interactomics models in terms of categories of Ł ukasiewicz logic Algebras and Lukasiewicz Topos Ł ukasiewicz Topos with an n-valued Ł ukasiewicz Algebraic Logic subobject classifier genetic network transformations in Carcinogenesis developmental processes and Evolution/ Evolutionary Biology Relational Biology of Archea yeast and higher eukaryotic organisms nonlinear dynamics in non-random hierarchic genetic networks proteomics coupled genomes via signaling pathways mechanisms of neoplastic transformations of cells and topological grupoid models of genetic networks in cancer cells natural transformations of organismic structures in Molecular Biology
2015/7/30
A new approach to the modular, complex systems analysis of nonlinear dynamics of arrested neural cell Differentiation--induced cell proliferation during organismic development and the analogous cell c...
Sublingual nucleotides and immune response to exercise
Immunoglobulin A Exercise Natural killer cell
2015/7/23
Evidence exists regarding the potential role of exogenous nucleotides as regulators of the immune function in
physically active humans, yet the potential use of nucleotides has been hindered by their...
Genetic Evidence for Regional Isolation of Pocillopora Corals from Moorea
Pocillopora Corals from Moorea Regional Isolation
2015/7/16
Pocillopora is one of the most abundant and widely distributed coral genera, with a geographic range spanning the entire tropical Pacific and Indian Oceans as well as the Red Sea and Arabian Gulf. Acr...
Dynamics of epigenetic remodeling in interspecies porcine zygotes
pig methylation iICSI zygote
2015/6/23
The process of active paternal chromatin demethylation after fertilization in the pig is not fully
understood and very inconsistent data have been published by different research groups. We have app...
Genetic diversity and relationship between genetic distance and geographical distance in 14 Chinese indigenous chicken breeds and red jungle fowl
genetic diversity microsatellite genetic distance
2015/6/8
Genetic diversity and the relationship between genetic distance and geographical distance in red jungle fowl and 14 Chinese indigenous chicken breeds were evaluated using 29 microsatellite loci. The n...
DNA microsatellite analysis of genetic diversity among Chinese indigenous laying-type ducks (Anas platyrhynchos)
duck PCR microsatellite
2015/6/8
The genetic polymorphisms of 17 microsatellites were investigated in four indigenous laying-type duck breeds in China. The average number of alleles (Na) and average rates of homozygotes of each breed...
Mitochondrial D-loop sequence variation among autochthonous horse breeds in Croatia
mtDNA genetic diversity horse
2015/6/8
Genetic variation in three Croatian coldblood horse populations was analysed using a sequence analysis of the proximal part (nt 15 498?5 821) of the D-loop region of mtDNA. Twenty unrelated horses wer...
Relationships between longevity and conformation traits in Czech Fleckvieh cows
cattle Czech Fleckvieh longevity
2015/6/8
The relationships between conformation and longevity traits were analysed in 58 493 Czech Fleckvieh cows first calved from 1994 to 2003. All cows were scored for conformation during the first lactatio...
Study of genetic differences among Slovak Tsigai populations using microsatellite markers
Slovak Tsigai sheep microsatellite markers genetic relationship
2015/6/8
In this study genetic diversity, population structure and genetic relationships of Tsigai populations in Slovakia were investigated using microsatellite markers. Altogether 195 animals from 12 populat...
The role of the Borrelia oxidative stress regulator protein in virulence gene expression of the Lyme disease spirochete
Borrelia burgdorferi, BosR RpoS
2015/5/21
The Lyme disease agent, Borrelia burgdorferi, has a complex system that allows it to thrive in the harsh and distinct environments of its tick vector and mammalian host. Although it has been known for...
Genetic studies of replication restart in Escherichia coli
DNA the genetic biological DNA damage protein chromosomes proteins to repair
2015/1/28
Faithful DNA replication is essential for all organisms to maintain genetic integrity. During the DNA replication, replications forks are frequently stalled or collapsed due to the encounter of DNA le...
多位点基因分型用于蓝氏贾第鞭毛虫遗传多样性的研究进展
多位点基因分型 聚集体
2015/3/11
蓝氏贾第鞭毛虫（简称贾第虫）是一种重要的人兽共患肠道原虫，宿主广泛。目前，种内有8个有效聚集体型。随着分子生物学技术的发展，多位点基因分型（multi-locus genotyping，MLG）技术被广泛用于贾第虫的研究。该文就MLG技术在阐述贾第虫遗传多样性、评估人兽共患传播的可能性及分类学上的应用研究作一综述。