搜索结果: 1-15 共查到“知识库 生物物理学 DNA”相关记录31条 . 查询时间(0.252 秒)
Numerical study of linear and circular model DNA chains confined in a slit: metric and topological properties
Numerical study linear and circular model DNA chains metric and topological properties Biological Physics
2012/4/20
Advanced Monte Carlo simulations are used to study the effect of nano-slit confinement on metric and topological properties of model DNA chains. We consider both linear and circularised chains with co...
DNA Self-Assembly and Computation Studied with a Coarse-grained Dynamic Bonded Model
DNA Self-Assembly Computation Studied Coarse-grained Dynamic Bonded Model Biological Physics
2012/5/3
We utilize a coarse-grained directional dynamic bonding DNA model [C. Svaneborg, Comp. Phys. Comm. (In Press DOI:10.1016/j.cpc.2012.03.005)] to study DNA self-assembly and DNA computation. In our DNA ...
Macroscopic loop formation in circular DNA denaturation
Macroscopic loop formation circular DNA denaturation Biomolecules Statistical Mechanics
2012/5/3
The statistical mechanics of DNA denaturation under fixed linking number is qualitatively different from that of the unconstrained DNA. Quantitatively different melting scenarios are reached from two ...
Entropy-Enthalpy Compensation May Be a Useful Interpretation Tool for Complex Systems Like Protein-DNA Complexes: An Appeal to Experimentalists
Entropy-Enthalpy Compensation Useful Interpretation Tool Complex Systems Protein-DNA Complexes Experimentalists
2012/2/28
In various chemical systems enthalpy-entropy compensation (EEC) is a well-known rule of behavior, although the physical roots of it are still not completely understood. It has been frequently question...
About the importance of the nuclear recoil in αemission near the DNA
nuclear recoil αemission DNA Nuclear Experiment
2011/8/17
Abstract: The effect of the energy deposition inside the human body made by radioactive substances is discussed. For the first time, we stress the importance of the recoiling nucleus in such reactions...
Abstract: This paper is devoted to the analysis of the complex damage of DNA irradiated by ions. The analysis and assessment of complex damage is important because cells in which it occurs are less li...
Stacking Interactions in Denaturation of DNA Fragments
Stacking Interaction Denaturation of DNA Fragments
2011/9/14
A mesoscopic model for heterogeneous DNA denaturation is developed in the framework of the path integral formalism. The base pair stretchings are treated as one-dimensional, time dependent paths contr...
Structural correlations and melting of B-DNA fibres
B-DNA fibres Structural correlations melting
2011/9/13
Despite numerous attempts, the understanding of the thermal denaturation of DNA is still a challenge due to the lack of structural data at the transition since standard experimental approaches to DNA ...
Folding and unfolding of a triple-branch DNA molecule with four conformational states
Nonequilibrium systems, single-molecule experiments,optical tweezers, DNA
2011/8/31
Single-molecule experiments provide new insights into biological processes hitherto not accessible by measurements performed on bulk systems. We report on a study of the kinetics of a triple-branch DN...
Transverse conductance of DNA nucleotides in a graphene nanogap from first principles
DNA nucleotides graphene nanogap principles
2011/1/5
The fabrication of solid-state nanopores is becoming increasingly sophisticated. Recently, nanopores were successfully created in graphene and translocation of DNA has been demonstrated. Taken togethe...
DNA waves and water
DNA waves water
2011/1/5
Some bacterial and viral DNA sequences have been found to induce low frequency electromagnetic waves in high aqueous dilutions. This phenomenon appears to be triggered by the ambient electromagnetic b...
Fluctuation Pressure Assisted Ejection of DNA From Bacteriophage
Fluctuation Pressure DNA From Bacteriophage
2011/1/6
The role of thermal pressure fluctuation excited within tightly packaged DNA prior to ejection from protein capsid shells is discussed in a model calculation. At equilibrium before ejection we assume ...
Using Monte-Carlo simulations, we deconvolved the sliding and hopping kinetics of GFP-LacI proteins on elongated DNA from their experimentally observed seconds-long diffusion trajectories. Our simulat...
DNA拓扑异构酶Ⅱ的多态转换模型
DNA拓扑异构酶Ⅱ 主方程 稳态 无机磷
2011/7/29
DNA拓扑异构酶Ⅱ是一种分子马达，它利用ATP水解产生的化学能，切断一条双链DNA片段(G segment)，并让另一条双链DNA片段(T segment)从缺口处通过。对DNA拓扑异构酶Ⅱ的工作循环研究将有助于阐明其工作机理。本文根据已有实验资料，利用主方程方法构建了DNA拓扑异构酶Ⅱ状态转变的随机跃迁模型，求得系统各态的稳态解。进而推导出稳态下无机磷(Pi)浓度随时间的变化，得到DNA拓扑异构...
p53-Mdm2相互作用在DNA损伤的细胞响应方面起着非常重要的作用。最新实验结果表明，在受到各种辐射损伤而引起DNA损伤后，细胞中的p53蛋白浓度在单体细胞和群体细胞情况下，表现为非衰减振荡和衰减振荡两种不同的动力学行为。通过研究p53 -Mdm2负反馈回路的非线性动力学，分析了各种（特别是DNA损伤，p53和Mdm2浓度三者之间的）动力学关系，提出了一个能同时描述这两种不同动力学行为的非线性模...