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旨在采用生物信息学方法筛选鸡IGF2基因中具有潜在生物学功能的非同义单核苷酸多态性(non-synonymous single nucleotide polymorphisms,nsSNPs)位点,为开展标记辅助选择改良鸡重要经济性状提供理论参考。本研究从dbSNP数据库中检索出鸡IGF2基因的12个nsSNPs位点,利用生物信息学软件SIFT、Polyphen-2、PhD-SNPSNAP预测其...
The effects of heat stress on HSP90B1 messenger RNA (mRNA) expression in the hypothalamus of chicken were investigated and HSP90B1 variations were detected. Females of two Chinese chicken breeds (Huai...
The goat Capra hircus is one of several economically important livestock in China. Advances in molecular genetics have led to the identification of several single nucleotide variation markers associat...
The purpose of this study was to investigate interaction effects of genes using a Harvester method. A sample of Korean cattle, Hanwoo (n = 476) was chosen from the National Livestock Research Institut...
A whole genome association (WGA) study was performed to detect significant polymorphisms for meat quality traits in an F2 cross population (N = 478) that were generated with Korean native pig sires an...
In this study, we investigated the relationship between unsaturated fatty acids influencing beef flavor and four types of SNPs (c.280A>G, c.388G>A, c.408G>C and c.456A>G) located at exon 2, 3 and 4 of...
Fatty acid composition of beef intramuscular tissue is an important trait because high proportions of mono-unsaturated fatty acid are related to favorable beef flavor. In this study, we investigated t...
In the past decade, there have been many advances in whole-genome sequencing in domestic animals, as well as the development of “next-generation” sequencing technologies and high-throughput genotyping...
为探讨鸡pre-microRNA SNP的多态性及其可能的功能意义, 对鸡471个pre-microRNA区域的SNP位点进行了鉴定和生物信息学分析。结果表明: pre-microRNA的SNP多态性显著地低于其侧翼区(P<0.01=, 其种子区SNP变异对pre-microRNA二级结构稳定性的影响高于其他各区; microRNA成熟体SNP可能影响microRNA对靶基因的选择。研究结果提示:...
As genetic markers, single nucleotide polymorphisms (SNP) are very appropriate for the development of genetic tests for economic traits in livestock. Several microsatellite markers have been identifie...
Leptin, the hormone product of the obese gene, is secreted predominately from white adipose tissue and regulates feed intake, energy metabolism and body composition. It has been considered a candidate...
Lipopolysaccharide binding protein (LBP) and CD14 protein play important roles in the defense against infection of Gram-negative bacteria. In the present study, tissue distribution and polymorphism of...
The myostatin gene of seven important meat (Beltex (Australia), BeltexHuyang (F1), Meat and Multi-Prolific Chinese Merino Fine Wool, Meat Chinese Merino Fine Wool and Dorper (South Africa)) an...
CCAAT/enhancer binding protein ??(C/EBP?? plays an important role in lipid deposition and adipocyte differentiation. In order to find genetic markers to improve the meat quality of Korean cattle, the ...
Carboxypeptidase E (CPE) plays an important role in the regulation of the body fat content. Therefore, it has been suggested as candidate gene for traits related to meat quality in beef cattle. This s...

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