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Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans
dietary protein protein source high-protein diet gut microbiota
2018/11/19
Background: Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for lar...
Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans
dietary protein protein source high-protein diet gut microbiota,
2018/11/16
Background: Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for lar...
Within-day protein distribution does not influence body composition responses during weight loss in resistance-training adults who are overweight
exercise weight loss muscle mass heart health protein patterning
2018/11/20
Background: Emerging research suggests that redistributing total protein intake from 1 high-protein meal/d to multiple moderately high-protein meals improves 24-h muscle protein synthesis. Over time, ...
Effect of weekly physical activity frequency on weight loss in healthy overweight and obese women attending a weight loss program: a randomized controlled trial
physical activity pattern obesity weight loss diet waist circumference cardiometabolic disease risk
2018/12/18
Background: The effect of intensity and duration of physical activity (PA) on weight loss has been well described. However, the effect of the frequency of weekly PA on weight loss is still unknown.
Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
insulin resistance leucine muscle mass inflammation amino acid transporters mTORC1
2018/12/14
Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle protein synthetic responses after the ingestion of a pr...
Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
insulin resistance leucine muscle mass inflammation amino acid transporters mTORC1
2018/12/18
Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle protein synthetic responses after the ingestion of a pr...
Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial
HOMA insulin resistance prediabetes IOM RDA high-dose vitamin D
2018/12/3
Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR).
Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men
body composition energy expenditure ketogenic diet insulin carbohydrate fat macronutrients
2018/12/3
Background: The carbohydrate–insulin model of obesity posits that habitual consumption of a high-carbohydrate diet sequesters fat within adipose tissue because of hyperinsulinemia and results in adapt...
Long-term effects of a randomized, controlled, tailor-made weight-loss intervention in primary care on the health and lifestyle of overweight and obese women
diet effectiveness exercise obesity randomized controlled trial
2018/11/30
Background: Maintenance of weight loss after a diet and exercise intervention is often low. Moreover, short follow-up periods and high attrition rates often impede translation of study results to clin...
A weight-loss program adapted to the menstrual cycle increases weight loss in healthy, overweight, premenopausal women: a 6-mo randomized controlled trial
menstrual cycle obesity weight loss hormonal fluctuations energy expenditure satiation energy restriction
2018/11/30
Background: Hormonal fluctuations during the menstrual cycle influence energy intake and expenditure as well as eating preferences and behavior.
Challenging the claim that intake of krill oil is associated with increased metabolic risk in overweight men
claim overweight men krill oil
2018/11/30
On 27 May 2015, the scientific study by Albert et al. (1) entitled “Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men” was published on...
Long-term magnesium supplementation improves arterial stiffness in overweight and obese adults: results of a randomized, double-blind, placebo-controlled intervention trial
magnesium, intervention study, arterial stiffness, pulse wave velocity, blood pressure
2018/11/29
Background: Epidemiologic studies have suggested a protective effect of magnesium intake on cardiovascular disease risk. However, intervention trials of magnesium supplementation on blood pressure and...
Effect of ω-3 supplementation on placental lipid metabolism in overweight and obese women
lipid metabolism ω-3 fatty acids placenta pregnancy obesity
2018/11/29
Background: The placentas of obese women accumulate lipids that may alter fetal lipid exposure. The long-chain omega-3 fatty acids (n–3 FAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) ...
Moderate weight loss in obese and overweight men preserves bone quality
bone caloric restriction men obesity sex steroids
2018/12/24
Background: Weight loss (WL) negatively affects bone mineral density (BMD) in older populations and has specifically been shown in women.
Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention
adiposity childhood obesity early life obesity lifecourse prevention
2018/12/20
Background: Early life may be a “critical period” when appetite and regulation of energy balance are programmed, with lifelong consequences for obesity risk. Insight into the potential impact of modif...