搜索结果: 1-15 共查到“知识库 理学 apoptosis”相关记录20条 . 查询时间(0.062 秒)
Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells
apoptosis endocycling cells p53 protein
2015/1/7
Apoptotic cell death is an important response to genotoxic stress that prevents oncogenesis. It is known that tissues can differ in their apoptotic response, but molecular mechanisms are little unders...
The role of mitochondria and proteasomes in T cell apoptosis
Cell apoptosis cell death cell biology enzyme hydrolysis T cells
2014/12/11
Apoptosis is a type of programmed cell death that is essential for the development and maintenance of tissue homeostasis in multicellular organisms. Because apoptosis is important in many biological s...
The effect of dominant negative EGR-1 and hyperbaric oxygen on immune cell apoptosis
Induction of cells and multicellular organisms physiology cell death cell research gene regulation
2014/12/11
The ultimate means of limiting the influence of an individual cell on the physiology of a multicellular organism is to induce the death of that cell. Apoptosis is a genetically regulated form of cell ...
The role of oxidative stress in apoptosis
Thymus cells thymus thymocyte apoptosis oxidative stress molecular oxygen oxidation of thiol
2014/12/11
Thymocytes undergo negative and positive selection during their development in the thymus. During this selection process, the majority of thymocytes are eliminated by apoptosis. In the first part of t...
TRAF-interacting protein, an inhibitor of the canonical nuclear factor-kappaB pathway, plays a key role in the estradiol -dependent apoptosis of the dual-phenotype gamma amino butyric acid/glutamate neurons in the anteroventral periventricular nucleus of the male rat
Mediated estradiol LH surge neurons male AVPV E2 - mediated cell death neurons
2014/12/11
The anteroventral periventricular nucleus (AVPV) of the preoptic area mediates the positive feedback effects of estradiol (E2) on LH surge in rats. Consistent with their role in female reproduction, t...
Notch 1 Mediated Inhibition of Nur77-induced apoptosis: Implications for T-cell Leukemia
Apoptosis Calcium IP3R Leukemia Notch1 Nur77
2014/12/10
It is widely accepted that activating mutations of genes encoding the Notch family of transmembrane receptors, specifically Notch1, are associated with oncogenic transformation. Previous data from our...
The Signaling Mechanism of TGF-β1 Induced Bovine Mammary Epithelial Cell Apoptosis
TGF-β1 ALK-5 p-Smad2/3 [Ca2+]i Mammary Epithelial Cell
2016/5/9
The present study showed that Transforming growth factor beta 1 (TGF-β1) can induce apoptosis of bovine mammary epithelial cells. This apoptosis was also observed with phosphorylation of Smad2/3 withi...
Influence of Nitric Oxide on Steroid Synthesis, Growth and Apoptosis of Buffalo (Bubalus bubalis) Granulosa Cells In vitro
Apoptosis Buffalo Granulosa Cell Nitric Oxide Steroidogenesis
2016/5/6
Objective of this study was to examine the effect of sodium nitroprusside (SNP), a nitric oxide (NO) donor on steroid synthesis, growth and apoptosis of buffalo granulosa cells (GCs) in vitro. Follicu...
Development of Signaling Echo Method for Cell-based Quantitative Efficacy Evaluation of Anti-cancer Drugs in Apoptosis without Drug Presence Using High-precision Surface Plasmon Resonance Sensing
Signaling Echo Method Cell-based Quantitative Efficacy Evaluation Anti-cancer Drugs
2010/9/20
We propose a rapid and label-free quantitative evaluation of anti-cancer drug efficacy in apoptosis using live cancer cells cultured on a sensor chip. The resultant custom-made, high-precision surface...
THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN INCREASES P34CDC2 PHOSPHORYLATION AND ENHANCES CELL SURVIVAL AND PROLIFERATION BY PROTECTING THE WEE1 KINASE FROM DEGRADATION BY CASPASE-3
p34Cdc2 Survivin Wee1 Caspase-3 Apoptosis
2015/5/21
The anti-apoptotic protein Survivin and the cyclin-dependent kinase p34Cdc2 are involved in cell cycle progression and apoptosis. Activation of Cdc2 is required for its pro-apoptotic activity, which c...
In vitro Arsanilic Acid Induction of Apoptosis in Rat Hepatocytes
Arsanilic Acid Apoptosis Antioxidant Enzymes Gene Expression
2016/4/21
This paper aimed to study the toxicity of arsanilic acid on rat primary hepatocytes in vitro by a modification of the perfusion method. The conditions included concentrations of 0, 1.085, 10.85, 108.5...
Involvement of Cathepsin D in Apoptosis of Mammary Epithelial Cells
Cathepsin D Apoptosis Mammary Epithelial Cells
2016/4/21
During involution of the mammary gland after the lactation period, the gland undergoes an extensive epithelial cell death. In our previous study, overexpression of an extracellular proteinase inhibito...
Effect of Cellular Zinc on the Regulation of C2-ceramide Induced Apoptosis in Mammary Epithelial and Macrophage Cell Lines
Zinc Cell Viability Apoptosis Immunity System
2016/4/20
Zinc is a trace element that is associated with a stimulation of immune function and regulation of ion balance for livestock production. In this study, the effect of zinc as inhibitor to apoptosis-ind...
Expression of the Antioxidant Enzyme and Apoptosis Genes in In vitro Maturation/In vitro Fertilization Porcine Embryos
Pig IVM/IVF Embryo RT-PCR Antioxidant Apoptosis
2016/4/14
This study was aimed at testing the gene expression of antioxidant enzymes and apoptosis genes for in vitro culture in porcine embryos produced by in vitro maturation/in vitro fertilization (IVM/IVF)....
Mitochondrial ATP-Sensitive Potassium Channel Activation Protects Cerebellar Granule Neurons From Apoptosis Induced by Oxidative Stress
Mitochondrial ATP-Sensitive Oxidative Stress
2014/3/31
ptosis contributes to ischemic injury in the brain,
4
and
brain mitochondria contain 7 times more mitoK
ATP
channels
than heart mitochondria.
5
Several reports have shown that
mitoKATP
chann...