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Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony
Deterministic stochastic aspects VEGF-A production
2011/1/5
A model is proposed to study the process of hypoxia-induced angiogenesis in cancer cells. The model accounts for the role played by the vascular endothelial growth factor (VEGF)-A in regulating the ox...
Some thoughts on the ontogenesis in B-cell immune networks
Some thoughts the ontogenesis B-cell immune networks
2011/1/5
We are interested in modeling theoretical immunology within a statistical mechanics flavor: focusing on the antigen-independent maturation process of B-cells, in this paper we try to revise the proble...
Asymptotic and bifurcation analysis of wave-pinning in a reaction-diffusion model for cell polarization
Asymptotic bifurcation analysis wave-pinning reaction-diffusion model
2011/1/5
We describe and analyze a bistable reaction-diffusion (RD) model for two interconverting chemical species that exhibits a phenomenon of wave-pinning: a wave of activation of one of the species is init...
Spontaneous contractility--mediated cortical flow generates cell migration in 3-dimensional environments
Spontaneous contractility--mediated cortical flow generates migration 3-dimensional environments
2010/11/15
We present a generic model of cell motility generated by acto-myosin contraction of the cell cortex. We identify analytically dynamical instabilities of the cortex and show that they trigger spontaneo...