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深圳北京大学香港科技大学医学中心詹启敏/崔永萍团队新发表在National Science Review杂志上的论文揭示了食管癌中免疫与肿瘤互作驱动的空间定向进化（图）
食管癌 死亡率 食管鳞状细胞癌
2024/7/9
目前，食管癌的发病率与死亡率在全球范围内均排在前列，超过一半以上的患者发生在我国，其中约90%的病理类型为食管鳞状细胞癌（esophageal squamous cell carcinoma，ESCC）。通过以往的研究发现，食管鳞癌在基因组变异和肿瘤微环境等方面均具有广泛的肿瘤异质性，而造成食管鳞癌异质性的原因尚不清楚。因此，充分了解肿瘤异质性的特征以及其形成机制将有助于指导食管鳞癌药物开发以及临...
Review of National and International Accreditation of Pharmacy Programs in the Gulf Cooperation Council Countries
international accreditation pharmacy education Gulf Cooperation Council (GCC) countries ACPE certification program national accreditation
2019/1/7
Objective. To compare the different philosophies, emphases and processes of national and international accreditation paths available to pharmacy programs in Gulf Cooperation Council (GCC) countries.To...
Effects of a National Cholesterol Education Program Step II Diet on apolipoprotein A-IV metabolism within triacylglycerol-rich lipoproteins and plasma
Apolipoprotein A-IV kinetics triacylglycerol-rich lipoproteins
2016/6/14
Apolipoprotein (apo) A-IV is a major component
of triacylglycerol-rich lipoprotein (TRL) apolipoproteins.
The National Center for Health Statistics reference and the growth of Indian adolescent boys
Growth anthropometry adolescents
2016/6/14
Few studies describing the growth of adolescents
exist because of the difficulties in interpreting anthropometric
data in this age group.
Lipid responses to plant-sterol-enriched reduced-fat spreads incorporated into a National Cholesterol Education Program Step I diet
table spread cholesterol plant sterols
2016/6/14
Plant sterol esters reduce cholesterol absorption
and lower circulating blood cholesterol concentrations when
incorporated into the habitual diet.
Serum retinyl esters are not associated with biochemical markers of liver dysfunction in adult participants in the third National Health and Nutrition Examination Survey (NHANES III), 1988–1994
Retinyl esters hypervitaminosis A liver function
2016/6/13
Serum retinyl ester concentrations are elevated in
hypervitaminosis A. It was suggested that retinyl esters > 10% of
total serum vitamin A indicate potential hypervitaminosis, but
this cutoff was d...
Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey
Cognitive function cognitive decline dementia
2016/6/13
High circulating total homocysteine (tHcy) concentrations
are associated with stroke, which is a major cause of
cognitive dysfunction. Blood homocysteine concentrations are
inversely correlated wit...
Serum retinol distributions in residents of the United States: third National Health and Nutrition Examination Survey, 1988–1994
Adults children females
2016/6/13
Inadequate vitamin A status has been a potential
nutritional problem for some segments of the US population,
particularly children and the poor.
National Institutes of Health workshop: Role of Nutrient Regulation of Signal Transduction in Metabolic Diseases
Signal Transduction Metabolic Diseases
2016/6/1
Nutritive and nonnutritive dietary constituents can promote or
hinder the development of several chronic diseases, including
cancer, obesity, inflammatory diseases, diabetes, and cardiovascular
dis...
Serum vitamin C concentrations and diabetes: findings from the third National Health and Nutrition Examination Survey, 1988–1994
diabetes mellitus diet surveys epidemiology
2016/5/31
Previous studies suggested that diabetes mellitus
may lower serum vitamin C concentrations, but most of these
studies used clinic-based populations with established diabetes
of varying duration and...
Resting energy expenditure in reduced-obese subjects in the National Weight Control Registry
Obesity weight loss body composition
2016/5/31
Weight loss in obese subjects is associated with a
reduction in resting metabolic rate (RMR). Whether the reduction
can be explained solely by a reduction in lean body mass
remains controversial.
Effects of the National Cholesterol Education Program's Step I and Step II dietary intervention programs on cardiovascular disease risk factors: a meta-analysis
NCEP Step I diet NCEP Step II diet total cholesterol
2016/5/31
Background: Plasma lipid and lipoprotein responses have been
variable in dietary intervention studies.Objective: The objective of this study was to evaluate the effects
of the National Cholesterol E...
Revisiting the effectiveness of the National Cholesterol Education Program's Step I and Step II diets: cholesterol-lowering diets in a pharmaceutically driven world
cholesterol-lowering Cholesterol Education Program's
2016/5/30
Cholesterol-lowering diets are the mainstay of therapy for
hypercholesterolemia. In this issue of the Journal, Kris-Etherton
et al present an important meta-analysis summarizing the effectiveness
o...
Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey
age sex race
2016/5/30
The elevation of circulating total homocysteine
concentrations in a fasting state is associated with an increased
risk of occlusive vascular disease.
Serum and red blood cell folate concentrations, race, and education: findings from the third National Health and Nutrition Examination Survey
Education ethnic group folic acid
2016/5/30
Little is known about the relations between race or
ethnicity, educational attainment, and serum and red blood cell folate
concentrations.