搜索结果: 1-15 共查到“生物学 Death”相关记录35条 . 查询时间(0.126 秒)
代谢重编程是肿瘤的基本特征之一。肿瘤细胞即使在氧气充足的条件下仍优先通过糖酵解途径而不是线粒体氧化磷酸化产生能量，这种现象被称为Warburg效应。这种异常的代谢方式导致肿瘤细胞过度依赖葡萄糖代谢产生乳酸，并同时抑制了三羧酸（TCA）循环等氧化代谢途径，减少了细胞内氧化压力并同时产生大量用于生物合成的代谢中间体，促进肿瘤细胞的快速增殖。肿瘤细胞如何协调糖酵解以及TCA循环也一直是肿瘤代谢领域的重点...
烟酰胺腺嘌呤二核苷酸（Nicotinamide Adenine Dinucleotide, NAD+）是细胞内重要的活性分子，它不仅是糖酵解、糖异生和三羧酸循环中多种代谢酶的辅因子，还直接作为底物参与多种蛋白质翻译后修饰过程，比如蛋白质去乙酰化。然而，由于NAD+的极性原因，其在细胞内各个区域之间不能自由穿梭，其中又以线粒体的NAD+含量最高，并且对线粒体的正常功能发挥着至关重要的作用。SLC25...
Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-kappa B mediated acute lung inflammation in mice
Electronic cigarette aerosol Acute lung inflammation Oxidative stress NF-κ b pathway Aldehyde
2023/6/21
Electronic cigarette (e-cigarette) use has been linked to recent acute lung injury case clusters in over 2000 patients and dozens of deaths in the United States, however, the mechanism leading to lung...
2022年1月21日，中国科学院上海营养与健康研究所章海兵研究组在国际学术期刊Cell Death and Differentiation在线发表了题为“Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia”的研究成果。该研究揭示...
近日，中南大学湘雅医院临床药理研究所张伟教授团队在细胞生物学权威期刊《Cell Death & Disease》（即时IF:8.104）上连续发表两篇鼻咽癌放疗基因组学原创性基础研究论著。
近日，山西医科大学山西省出生缺陷和细胞再生重点实验室解军教授团队在 《Cell Death & Disease》杂志发表了最新研究成果“Aberrant Gcm1 expression mediates Wnt/β-catenin pathway activation in folate deficiency involved in neural tube defects”。
千淘万漉虽辛苦，吹尽狂沙始到金—记本科学员鲁洪廷、封仁乾与唐佳坤在《Cell Death & Disease》发表论文
Cell Death & Disease；较大影响力；刊物
2021/11/12
近日，空军军医大学基础医学院临床医学系2016级本科学员鲁洪廷、封仁乾，2017级学员唐佳坤在生理与病理生理学教研室周京军教授的指导下，所完成论文“CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts”被《cell death & disease》刊用，该期刊属于Nature出版...
天津医科大学宣成昊教授课题组《Cell Death Differ》揭示JMJD6以不依赖于其酶活性的方式调控DNA损伤应答的分子机制
天津医科大学 宣成昊 教授 Cell Death Differ JMJD6 不依赖 酶活性 DNA 损伤应答 分子机制
2019/10/24
天津医科大学基础医学院宣成昊教授课题组最近报道了JMJD6以不依赖于其酶活性的方式调控DNA损伤应答，相关研究成果于2019年7月发表在《Cell Death Differ》（2018年影响因子8.086，5年影响因子8.309），题目为“JMJD6 modulates DNA damage response through downregulating H4K16ac independently...
Study reveals how collapse of protein processes is driver of aging and death（图）
Study reveals collapse protein processes driver aging and death
2019/10/28
Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study published in Proceedings of the National Academy of Sciences (PNAS)...
天津医科大学王宝利研究员课题组《Cell Death Differ》揭示长链非编码RNA调节骨髓基质干细胞骨向分化的机制
天津医科大学 王宝利 研究员 长链非编码RNA 骨髓基质 干细胞 骨向分化机制
2019/3/19
天津医科大学代谢病医院内分泌研究所王宝利研究员课题组最近报道了长链非编码RNA PGCβ-OT1 通过拮抗miR-148a-3p调节骨髓基质干细胞成骨-成脂分化平衡的作用机制。相关研究成果于2019年2月在线发表在《Cell Death Differ》 （2017年影响因子8；5年影响因子7.999），题目为“A novel long noncoding RNA PGC1β-OT1 regulat...
2018年冷泉港亚洲会议：Iron,Reactive Oxygen Species&Ferroptosis in Life,Death&Disease（Cold Spring Harbor Asia conference on Iron,Reactive Oxygen Species&Ferroptosis in Life,Death&Disease）
2018年 冷泉港亚洲会议 Iron,Reactive Oxygen Species&Ferroptosis in Life,Death&Disease
2018/1/12
We are pleased to announce the Cold Spring Harbor Asia conference on Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease which will be held in Suzhou, China, located approximately 60 ...
2018年冷泉港亚洲会议（Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease）
Fe(II) Fe(III) H2O2
2017/12/28
We are pleased to announce the Cold Spring Harbor Asia conference on Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease which will be held in Suzhou, China, located approximately 60 ...
浙江大学生命科学研究院张龙实验室在Cell Death & Differentiation发表论文阐述SUMO介导的核受体泛素化调控巨噬细胞凋亡（图）
浙江大学生命科学研究院 张龙实验室 Cell Death & Differentiation SUMO介导 核受体泛素化 巨噬细胞凋亡
2017/7/6
2017年6月16日，张龙实验室在Cell Death & Differentiation发表题为“SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death”的研究论文，揭示SUMO介导的核受体泛素化调控巨噬细胞凋亡。孤核受体NR4A1（nuclear receptor subfamily4,group A,memb...
2017 细胞死亡和炎症 Keystone Symposia （2017 Keystone Symposia on Cell Death and Inflammation）
2017细胞死亡和炎症Keystone Symposia
2017/3/10
Cell death has long been known to be an important instigator of inflammation in sterile injury, as well as an amplifying factor in infection-associated inflammation, but the specific molecules underpi...
Extreme temperatures threaten desert songbirds with death by dehydration
Extreme temperatures threaten desert songbirds death by dehydration
2017/3/13
According to NASA, 2016 was the hottest year on historical record. Globally, the increase amounted to nearly 1.8 degrees Fahrenheit. And while that might not sound like much of an increase, it could m...